Results 121 to 130 of about 31,208 (318)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
An extension and numerical analysis of the Hohmann spiral transfer [PDF]
, 2012 This paper extends previous work on the Hohmann Transfer Spiral (HST) by introducing a plane change into the analysis. An analytical expression determining the critical specific impulse incorporating a plane change is derived for both a circular and ...
Macdonald, Malcolm, Owens, Steven Robert
core
Generation of optimal trajectories for Earth hybrid pole sitters [PDF]
, 2011 A pole-sitter orbit is a closed path that is constantly above one of the Earth's poles, by means of continuous low thrust. This work proposes to hybridize solar sail propulsion and solar electric propulsion (SEP) on the same spacecraft, to enable such a ...
Colin R. McInnes +5 more
core +1 more source
The Dynamical History of HIP-41378 f—Oblique Exorings Masquerading as a Puffy Planet
The Astrophysical JournalThe super-puff HIP-41378 f represents a fascinating puzzle due to its anomalously low density on a far-out orbit in contrast with other known super-puffs.
Tiger Lu +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Spatiotemporal modulation of ultrafast plasmonic vortices with spin–orbit coupling
New Journal of PhysicsThe vortex field of surface plasmon polariton with orbital angular momentum (OAM), called plasmonic vortex, has played an important role in various research fields.
Weipeng Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Multi-objective optimisation of many-revolution, low-thrust orbit raising for Destiny mission [PDF]
, 2013 This work will present a Multi-Objective approach to the design of the initial, Low-Thrust orbit raising phase for JAXA’s proposed technology demonstrator mission DESTINY.
Kawakatsu, Yasuhiro +2 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Journal of Aerospace Technology and Management, 2015 Actual, important problems of space dynamics are related to the protection of the Earth and its close space environment. This includes the study of disposal strategies for artificial satellites, the real-time propagation of space catalogues of thousands
Martin Lara +3 more
doaj