Results 111 to 120 of about 142,311 (289)

Determination of GPS orbits to submeter accuracy [PDF]

Orbits for satellites of the Global Positioning System (GPS) were determined with submeter accuracy. Tests used to assess orbital accuracy include orbit comparisons from independent data sets, orbit prediction, ground baseline determination, and formal ...
Bertiger, W. I., Katsigris, E. C., Lichten, S. M.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Digital Twin-Driven TLE Error Correction for Precise LEO Satellite Orbit Prediction

Aerospace
Low earth orbit (LEO) satellite orbit prediction is one of the key measures to compensate for position errors and ensure position accuracy, which plays an important role in the aerospace communication network for undertaking functions such as routing ...
Xinchen Xu, Hong Wen, Wenjing Hou, Liang Chen, Yingwei Zhao, Tian Liu   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Expandable Orbit Decay Prediction Using Continual Learning

International Journal of Aerospace Engineering
Very low earth orbit (VLEO) spacecraft have become an attractive proposition with obvious advantages in various missions, including communication and ground observation.
Junhua He, Hua Wang, Haitao Wang, Xuankun Fang, Chengyi Huo   +4 more
doaj   +1 more source

Orbit Predictions for CHAMP and GRACE

, 2010
The orbit prediction system of GFZ is an indispensable tool for Satellite Laser Ranging (SLR) stations tracking the satellites CHAMP, GRACE-A/B, and TerraSAR-X, for providing orbit information for initial processing of mission data, and for the purpose of mission operations.
Snopek, K., König, D., König, R.
openaire   +4 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

An Improved Laplace Satellite Tracking Method Based on the Kalman Filter

Aerospace
When photoelectric measuring equipment is used to track satellites, the extraction of the short-term or long-term target often fails because the target is weak, clouds block the target, and/or the sun’s angle is too small, resulting in the loss of the ...
Shuang Cui, Jiang Li, Yang Yu, Ye Wang, Yuan Gao, Lei Zhang, Jiayu Chen   +6 more
doaj   +1 more source