Results 71 to 80 of about 1,734,402 (280)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Applied SciencesIn order to solve the problems of low tracking accuracy of in-orbit satellites by ground stations and slow processing speed of satellite target tracking images, this paper proposes an orbital satellite regional tracking and prediction model based on ...
Shuai Wang +7 more
doaj +1 more source
Development of On-orbit Predictions for the Middeck Active Control Experiment
IFAC Proceedings Volumes, 1994 Abstract The modeling and control design issues associated with a change in the operating environment are discussed for the Middeck Active Control Experiment (MACE): a Shuttle program scheduled for flight on STS-67, January 1995. MACE has been designed to investigate the extent to which the on-orbit behavior of flexible spacecraft can be predicted ...
J.P. How, D.W. Miller
openaire +1 more source
On the predictability and robustness of Galileo disposal orbits [PDF]
Celestial Mechanics and Dynamical Astronomy, 2019 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
David J. Gondelach +2 more
openaire +5 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Assessment of numerical differentiation methods for kinematic orbit solution of the GRACE mission [PDF]
, 2013 textThe historical method of precise orbit determination is a dynamic approach. However, with the improvement of GPS tracking data and associated tracking networks, two newer methods have been developed: reduced-dynamic and kinematic.
Krishnan, Sandeep Kalyanapuram
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Visual Navigation For On-Orbit Servicing Missions [PDF]
, 2013 Increasing complexity and costs of satellite missions promote the idea of looking for opportunities to extend the operational lifetime or to improve the performance of a satellite instead of simply replacing it by a new one.
Tzschichholz, Tristan +2 more
core
Observation of two distinct cold, dense ion populations at geosynchronous orbit: Local time asymmetry, solar wind dependence and origin [PDF]
, 2006 International audienceWe report on the observation of two distinct cold (TiNi>2 cm?3) ion populations at geosynchronous orbit. A statistical study was performed on measurements from the geosynchronous Los Alamos plasma instruments, for the period 1990 ...
Aasnes, A. +17 more
core +2 more sources