Results 81 to 90 of about 1,844,811 (291)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

An accuracy and speed comparison of the Vinti and Brouwer orbit prediction methods [PDF]

, 1969
Accuracy and speed comparison between drag-free and numerical satellite orbit prediction ...
Watson, S., Bonavito, N. L., Walden, H.
core  

Optimal design of the long-term LEO almanac by considering the atmosphere drag effects

Geo-spatial Information Science
Almanac is an elegant design to help Global Navigation Satellite Systems (GNSS) signal acquisition, which has been adopted by all global satellite navigation systems. For the future low Earth orbit (LEO) navigation constellation, the almanac will be more
Xueli Guo, Lei Wang, You Li
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Visual Navigation For On-Orbit Servicing Missions [PDF]

, 2013
Increasing complexity and costs of satellite missions promote the idea of looking for opportunities to extend the operational lifetime or to improve the performance of a satellite instead of simply replacing it by a new one.
Tzschichholz, Tristan, Boge, Toralf, Benninghoff, Heike   +2 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Improving Orbit Prediction of the Two-Line Element with Orbit Determination Using a Hybrid Algorithm of the Simplex Method and Genetic Algorithm

Aerospace
With the rapidly increasing number of satellites and orbital debris, collision avoidance and reentry prediction are very important for space situational awareness.
Jinghong Liu, Chenyun Wu, Wanting Long, Bo Yuan, Zhengyuan Zhang, Jizhang Sang   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Assessment of numerical differentiation methods for kinematic orbit solution of the GRACE mission [PDF]

, 2013
textThe historical method of precise orbit determination is a dynamic approach. However, with the improvement of GPS tracking data and associated tracking networks, two newer methods have been developed: reduced-dynamic and kinematic.
Krishnan, Sandeep Kalyanapuram
core