Results 61 to 70 of about 142,311 (289)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Short‐Time Prediction of Thermospheric Mass Density Based on Ensemble‐Transfer Learning

Space Weather, 2023
Reliable short‐time prediction of thermospheric mass density along the satellite orbit is always essential but challenging for the operation of Low‐Earth orbit satellites.
Peian Wang, Zhou Chen, Xiaohua Deng, Jing‐Song Wang, Rongxing Tang, Haimeng Li, Sheng Hong, Zhiping Wu   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

An Autonomous Orbit Prediction Approach for BDS MEO Satellites Using a Short-Sequence Adaptive Model

Remote Sensing
The new-generation global navigation satellite system (GNSS) demands enhanced satellite autonomy, where high-precision orbit prediction plays a pivotal role. Traditional dynamic models depend heavily on long-term on-orbit observations, making hybrid deep-
Yihui Zhao, Yuebo Ma, Hongfeng Long, Rujin Zhao, Xia Lin   +4 more
doaj   +1 more source

Orbit Prediction using Broadcast Ephemeris for GLONASS Satellite Visibility Analysis [PDF]

Journal of Astronomy and Space Sciences, 2009
Even though there are several Global Navigation Satellite Systems under development, only GPS and GLONASS are currently available for satellite positioning.
Hye-In Kim, Kwan-Dong Park
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Proposed Orbital Products for Positioning Using Mega-Constellation LEO Satellites

Sensors, 2020
With thousands of low Earth orbit (LEO) satellites to be launched in the near future, LEO mega-constellations are supposed to significantly change the positioning and navigation service for ground users.
Kan Wang, Ahmed El-Mowafy
doaj   +1 more source

Improved orbit predictions using two-line elements

, 2010
The density of orbital space debris constitutes an increasing environmental challenge. There are three ways to alleviate the problem: debris mitigation, debris removal and collision avoidance.
Alfriend, Boers, Boyce, Coffey, Creon Levit, Danielson, Flohrer, Gilbreath, Hedin, Kessler, Legendre, Liou, Liou, Neal, Pearlman, Ries, Schumacher, Snow, Wang, William Marshall   +19 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source