Results 101 to 110 of about 86,122 (316)

Self-organising satellite constellation in geostationary Earth orbit [PDF]

, 2015
This paper presents a novel solution to the problem of autonomous task allocation for a self-organizing satellite constellation in Earth orbit. The method allows satellites to cluster themselves above targets on the Earth’s surface.
Colombo, Camilla, Mingotti, Giorgio, McInnes, Colin, Mushet, Garrie   +3 more
core   +1 more source

Blockchain-based heterogeneous resource configuration scheme in computing power network

Scientific Reports
To provide users with on-demand computing and network resources while ensuring service quality, the concept of a computational power network has emerged.
Qiang Gao, Chunyu Liu, Lei Wang, Yiqing Liu, Yueqiang Xu   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Autonomy for Active Space Debris Removal: Research Issues and Approaches

, 2013
Even though the infinite vastness of the universe is an accepted theory, apparently infinity ends when it comes to orbits surrounding the Earth. This was a hard lesson to learn when Iridium 33 and Cosmos 2251 collided in the low Earth orbit in February ...
Förstner, Roger, Peters, Susanne, Fiedler, Hauke   +2 more
core  

Towards robust aero-thermodynamic predictions for re-usable single-stage to orbit vehicles

, 2012
Re-usable single stage to orbit launch vehicles promise to reduce the cost of access to space, but their success will be particularly reliant on accurate and robust modelling of their aero-thermodynamic characteristics.
Abdul Ahmad, Wuilbercq, Romain, Scanlon, Thomas, Romain Wuilbercq, Ahmad, Abdul Ossman, Thomas Scanlon, Richard Brown, Brown, Richard   +7 more
core   +1 more source

Partial actions on quotient spaces and globalization

Applied General Topology
Given a partial action of a topological group G on a space X we determine properties P which can be extended from X to its globalization. We treat the cases when P is any of the following: Hausdorff, regular, metrizable, second countable, and having ...
Luis Martínez, Héctor Pinedo, Andrés Villamizar   +2 more
doaj   +1 more source

A Review of the Space Environment Effects on Spacecraft in Different Orbits

IEEE Access, 2019
The space environment consists of various complex phenomena, which could have a strong influence on the spacecraft operation in different aspects. Since the very beginning of space exploration, numerous studies have been done on the space environment ...
Yifan Lu, Qi Shao, Honghao Yue, Fei Yang
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

CUSTARD (Cranfield University Space Technology Advanced Research Demonstrator) - A Micro-System Technology Demonstrator Nanosatellite. Summary of the Group Design Project MSc in Astronautics and Space Engineering. 1999-2000, Cranfield University [PDF]

, 2003
CUSTARD (Cranfield University Space Technology And Research Demonstrator) was the group design project for students of the MSc in Astronautics and Space Engineering for the Academic Year 1999/2000 at Cranfield University. The project involved the initial
Turner, Ray, Hobbs, Stephen
core