Results 71 to 80 of about 4,035,131 (289)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

DLR’s Advanced Telerobotic Concepts and Experiments for On-Orbit Servicing [PDF]

, 2007
Summary. Space robotics will become a key technology for the exploration of outer space and the operation and maintenance of space stations, satellites and other plat-forms, saving costs and relieving man from dangerous tasks.
Hirzinger, Gerd, Landzettel, Klaus, Reintsema, Detlef, Klaus L, Gerd Hirzinger, Detlef Reintsema   +5 more
core  

Training networks without wavefront label for pixel-based wavefront sensing

Frontiers in Physics
Traditional image-based wavefront sensing often faces challenges in efficiency and stagnation. Deep learning methods, when properly trained, offer superior robustness and performance.
Yuxuan Liu, Yuxuan Liu, Yuxuan Liu, Xiaoquan Bai, Xiaoquan Bai, Boqian Xu, Boqian Xu, Chunyue Zhang, Chunyue Zhang, Yan Gao, Yan Gao, Shuyan Xu, Shuyan Xu, Guohao Ju, Guohao Ju   +14 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

WFMHT Method of Orbit Maneuver Detection Based on Space-Based Bearing-Only Measurement [PDF]

Xibei Gongye Daxue Xuebao, 2018
The method of orbit maneuver detection of space targets is investigated using the space-based bearing-only measurement, which aims to acquire a real-time or nearly real-time awareness of orbit maneuver in the space situation awareness.

doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Modeling and Analysis of Bio-Inspired, Reconfigurable, Piezo-Driven Vibration Isolator for Spacecraft

Biomimetics
The positioning accuracy of spacecraft in orbit is easily affected by low-frequency micro-vibrations of the environment and internal disturbances caused by the payload.
Yubo Zhang, Lintao Wang, Lin Li, Xiaoming Wang, Shuai He   +4 more
doaj   +1 more source

A model of quotient spaces

Topological Algebra and its Applications, 2017
Let R be an open equivalence relation on a topological space E. We define on E a new equivalence relation ̃ℜ̅ by x̃ ̃ℜ̅y if the closure of the R-trajectory of x is equal to the closure of the R-trajectory of y.
Hattab Hawete
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source