Results 21 to 30 of about 11,324,813 (340)

Effects of miR-672 on the angiogenesis of adipose-derived mesenchymal stem cells during bone regeneration

Stem Cell Research & Therapy, 2021
Background Sufficient vascular network plays an important role in the repair of bone defects. Bone morphogenetic protein 2 (BMP2) being a key regulator of angiogenesis has attracted the attention of researchers.
Mingjiao Chen, Meng Zhou, Yao Fu, Jin Li, Zi Wang   +4 more
doaj   +1 more source

Functional Studies of Novel FOXL2 Variants in Chinese Families With Blepharophimosis–Ptosis–Epicanthus Inversus Syndrome

Frontiers in Genetics, 2021
The blepharophimosis–ptosis–epicanthus inversus syndrome (BPES) is a rare autosomal dominant disease mainly caused by FOXL2 variants. This genetic disorder is usually characterized by eyelid malformation and ovarian dysfunction.
Fang Li, Fang Li, Huifang Chen, Huifang Chen, Yefei Wang, Yefei Wang, Jie Yang, Jie Yang, Yixiong Zhou, Yixiong Zhou, Xin Song, Xin Song, Jiayan Fan, Jiayan Fan   +13 more
doaj   +1 more source

Retrospective Case Analysis of Transnasal Endoscopic Resection of Benign Orbital Apex Tumors: Some Thoughts on Transnasal Endoscopic Surgery

Journal of Ophthalmology, 2021
Purpose. To deeply discuss the patient selection, surgical planning, surgical techniques, and the therapeutic challenge for endoscopic transnasal resection of benign orbital apex tumors (OATs). Methods.
Cheng Li, Yang Gao, Rongxin Chen, Chao Cheng, Pan Yin, Zhihui Zhang, Yinghao Wang, Yuekun Bao, Huan Ma, Jianbo Shi, Rong Lu   +10 more
doaj   +1 more source

Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]

, 2020
The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA, Avunduk, Sibel, Basilico, Nicoletta, CASERTANO, MARCELLO, FATTORUSSO, CATERINA, Gimmelli, Roberto, Guidi, Alessandra, IMPERATORE, CONCETTA, LUCIANO, PAOLO, MENNA, MARIALUISA, Parapini, Silvia, PERSICO, MARCO, Ruberti, Giovina, Saccoccia, Fulvio   +13 more
core   +1 more source

Oncometabolites drive tumorigenesis by enhancing protein acylation: from chromosomal remodelling to nonhistone modification

Journal of Experimental & Clinical Cancer Research, 2022
Metabolites are intermediate products of cellular metabolism catalysed by various enzymes. Metabolic remodelling, as a biochemical fingerprint of cancer cells, causes abnormal metabolite accumulation.
Yidian Fu, Jie Yu, Fang Li, Shengfang Ge
doaj   +1 more source

Management of Unsatisfactory Postoperative Double Eyelid With Intralesional Corticosteroid Injection

Frontiers in Medicine, 2021
Purpose: The present study was designed to observe the curative effect of early intralesional corticosteroid injection to treat unsatisfactory double eyelid.Methods: This retrospective, observational study included 30 female patients (age 22–35 years ...
Siyi Zhang, Siyi Zhang, Yixiong Zhou, Yixiong Zhou, Fei Yu, Fei Yu, Dan Yan, Dan Yan, Yan Yan, Yan Yan, Meng Zhou, Meng Zhou, Yao Fu, Yao Fu, Yang Lu, Yang Lu   +15 more
doaj   +1 more source

Sino-orbital mucormycosis in a COVID-19 patient: A case report

International journal of surgery case reports, 2021
Introduction We report a case of post COVID-19 Sino-orbital Mucormycosis infection caused by Rhizopus oryzae and its management. Presentation of case The patient was diagnosed with COVID-19 and treated according to the persisting protocols.
Aastha Maini, G. Tomar, Deepak Khanna, Y. Kini, Hardik Mehta, V. Bhagyasree   +5 more
semanticscholar   +1 more source

Oncolytic Virotherapy: From Bench to Bedside

Frontiers in Cell and Developmental Biology, 2021
Oncolytic viruses are naturally occurring or genetically engineered viruses that can replicate preferentially in tumor cells and inhibit tumor growth. These viruses have been considered an effective anticancer strategy in recent years.
Ludi Yang, Ludi Yang, Xiang Gu, Xiang Gu, Jie Yu, Jie Yu, Shengfang Ge, Shengfang Ge, Xianqun Fan, Xianqun Fan   +9 more
doaj   +1 more source

Epigenetic drug library screening reveals targeting DOT1L abrogates NAD+ synthesis by reprogramming H3K79 methylation in uveal melanoma

Journal of Pharmaceutical Analysis, 2023
Uveal melanoma (UM) is the most frequent and life-threatening ocular malignancy in adults. Aberrant histone methylation contributes to the abnormal transcriptome during oncogenesis.
Xiang Gu, Yu Hua, Jie Yu, Ludi Yang, Shengfang Ge, Renbing Jia, Peiwei Chai, Ai Zhuang, Xianqun Fan   +8 more
doaj   +1 more source

Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis

Frontiers in Cell and Developmental Biology, 2021
Melanoma cells exhibit increased aerobic glycolysis, which represents a major biochemical alteration associated with malignant transformation; thus, glycolytic enzymes could be exploited to selectively target cancer cells in cancer therapy.
Xia Ding, Xia Ding, Lihua Wang, Lihua Wang, Mingjiao Chen, Mingjiao Chen, Yue Wu, Yue Wu, Shengfang Ge, Shengfang Ge, Jin Li, Jin Li, Xianqun Fan, Xianqun Fan, Ming Lin, Ming Lin   +15 more
doaj   +1 more source