Results 31 to 40 of about 2,555,963 (302)

Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis

open access: yesFrontiers in Genetics, 2022
This study was designed to identify differently expressed circular RNAs (circRNAs) and investigate their potential roles in lacrimal sacs from patients with chronic dacryocystitis.
Yue Li   +11 more
doaj   +1 more source

FBXO38 regulates ocular melanoma proliferation through the PI3K-Akt signaling pathway

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To investigate the effect of F-box only protein 38 (FBXO38) on the ocular melanoma proliferation and the potential regulatory pathway.Methods·Human skin cutaneous melanoma A375 and human uveal melanoma OMM2.3 cell lines with FBXO38 knockdown ...
WU Yijia   +5 more
doaj   +1 more source

Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

open access: yesCancer Biology & Medicine, 2021
Objective: Patients with underlying diseases are more vulnerable to coronavirus disease 2019 (COVID-19). The purpose of this study was to investigate cancer incidence in patients with COVID-19 and to determine whether cancer was associated with mortality
Ludi Yang   +3 more
doaj   +1 more source

Novel insight into RNA modifications in tumor immunity: Promising targets to prevent tumor immune escape

open access: yesThe Innovation, 2023
An immunosuppressive state is a typical feature of the tumor microenvironment. Despite the dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumor cell escape from immune surveillance, primary and acquired resistance have ...
Yuxin Kong   +3 more
doaj   +1 more source

Identification of immune hub genes participating in the pathogenesis and progression of Vogt-Koyanagi-Harada disease

open access: yesFrontiers in Immunology, 2022
BackgroundVogt-Koyanagi-Harada (VKH) disease is an autoimmune inflammatory disorder characterized by bilateral granulomatous uveitis. The objective of this study was to identify immune hub genes involved in the pathogenesis and progression of VKH disease.
Yiqi Wang   +14 more
doaj   +1 more source

Maraviroc attenuates orbital remodeling, inflammation, and lipid dysregulation in a murine model of thyroid eye disease associated with Graves’ disease

open access: yesFrontiers in Endocrinology
BackgroundGraves’ disease (GD) is an autoimmune condition that can extend beyond the thyroid, leading to thyroid eye disease (TED), a disorder marked by orbital inflammation and tissue remodeling.MethodsWe explored the therapeutic potential of maraviroc,
Fahimeh Hashemi Arani   +9 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Effect of Transcutaneous Upper Eyelid Blepharoplasty on Blink Parameters and Lipid Layer Thickness

open access: yesFrontiers in Medicine, 2021
Purpose: This study aimed to investigate the effect of transcutaneous upper eyelid blepharoplasty on lipid layer thickness (LLT) and blink parameters in young women during the early postoperative period.Methods: This prospective study included 110 eyes ...
Siyi Zhang   +9 more
doaj   +1 more source

Orbital ordering in the layered manganites [PDF]

open access: yes, 2006
The interaction between the long range correlations of electrons and the encompassing crystal structure is a key aspect of solid state physics. This thesis studies the long range interactions of the 3D orbitals in the single and bilayered manganites ...
Beale, Thomas ? W, Beale, Thomas Α. W.
core  

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

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