Results 71 to 80 of about 599,612 (252)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Managing eye injuries

, 2016
Based on what you found during the eye examination, classify the injury as a non-mechanical injury (chemical or thermal injury), a non-globe injury (orbital or adnexal injury) or as a mechanical globe injury.
Nyawira Mwangi, Dorothy Mutie
core  

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Clinical and radiological factors in traumatic open-globe injuries operated via primary enucleation, evisceration versus primary repair in Somalia

BMC Ophthalmology
Background Traumatic eye injuries are an important cause of visual impairment and can significantly affect patients’ quality of life. Accounting for approximately 7% of all bodily injuries and 10–15% of ocular diseases, traumatic eye injuries pose a ...
Kenan Calisir, Hassan Muhumed Mohamed, Aisha Abdirahman Yussuf, Cihan Celik   +3 more
doaj   +1 more source

Review of Ocular Injuries in Patients with Orbital Wall Fractures: A 5-Year Retrospective Analysis

Clinical Ophthalmology, 2020
Stephanie B Terrill,1 Hyelin You,2 Heidi Eiseman,1 Michael E Rauser1 1Department of Ophthalmology, Loma Linda University Eye Institute, Loma Linda, CA, USA; 2Department of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA ...
Terrill SB, You H, Eiseman H, Rauser ME
doaj  

Traffic injuries [PDF]

, 2014
Covers OCLC #1338688431, OCLC #1338688038"Serious Traffic Injuries: Serious Traffic injuries per 100 million vehicle miles traveled.""Traffic Injuries: Traffic injuries per 100 million vehicle miles traveled."Merged with: Traffic fatalities to form ...

core  

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Incidence and severity of asymptomatic ocular injury in adult and pediatric orbital fractures

, 2022
To evaluate the incidence of severe ocular injury requiring emergent ophthalmic evaluation in visually asymptomatic patients presenting with orbital fractures. We performed a retrospective chart review of all adult and pediatric orbital fractures between
Azraa Ayesha (13019492), Douglas P. Marx (9026483), Ben J. Brintz (9504825), Esteban Peralta (13019489), Abigail Jebaraj (13019495), Tyler Etheridge (6871898), Michael S. Jensen (13019486)   +6 more
core   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Water balloon-induced orbital fracture in an aviator

Military Medical Research, 2019
Background Orbital fractures are common injuries found in facial trauma. Typical etiologies of orbital fractures include motor vehicle collisions and assault. We report the case of a 32-year-old male who suffered an orbital fracture from a water balloon.
Timothy E. Holland, David M. Smith, Guy N. Gibson, Jared G. Brinkerhoff   +3 more
doaj   +1 more source