Results 61 to 70 of about 599,612 (252)

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

An Exceptional Case of Blow-Out Fracture with Complete Globe Dislocation into the Maxillary Sinus: Diagnostic Imaging and Surgical Reconstruction

Diagnostics
Orbital floor fractures are primarily caused by blunt trauma to the area around the eyes. These injuries most commonly affect the orbital floor and medial wall due to the fragility of these structures.
Krzysztof Gąsiorowski, Michał Gontarz, Jakub Bargiel, Tomasz Marecik, Grażyna Wyszyńska-Pawelec   +4 more
doaj   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source

Secondary Treatment of Naso-orbital Ethmoid Injuries

, 2017
Central midface fractures should be treated early due to their propensity for secondary devastating and disfiguring consequences. For example, the expected sequelae to inadequately repaired naso-orbital ethmoid (NOE) injuries include shortened retruded ...
Alan Herford
core   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

A novel face-level blast mechanism: CT findings of neuro-ocular injury from a mass-casualty event

BMC Medical Imaging
Background On September 17, 2024, thousands of handheld communication devices detonated simultaneously across Lebanon, producing a mass-casualty event with an unprecedented close-proximity blast mechanism.
Christel Tamer, Diana Abou Ltaif, Taima Ghalayini, Omar El Sardouk, Joe Rizkallah, Farah Abou Zeid, Aya El Harake, Hassan Cherri, Alain Abi Ghanem, Roula Hourani   +9 more
doaj   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Isolated traumatic orbital floor fracture: An analysis of the National Trauma Data Bank

World Journal of Otorhinolaryngology-Head and Neck Surgery
Objectives To date, no study provides a comprehensive analysis of traumatic orbital floor fractures across the United States. We aimed to characterize patient demographics, injury‐related variables, and operative management in this population. Method The
Emma De Ravin, Katherine Xu, Christian Fritz, Harman S. Parhar, Karthik Rajasekaran   +4 more
doaj   +1 more source

Early Reconstruction of Orbital Roof Fractures: [PDF]

Archives of Plastic Surgery, 2012
Background Orbital roof fractures are frequently associated with a high energy impactto the craniofacial region, and displaced orbital roof fractures can cause ophthalmic andneurologic complications and occasionally require open surgical intervention ...
Han Koo Kim, Jin Woo Kim, Tae Hui Bae, Woo Seob Kim   +3 more
doaj