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Orbitofrontal cortex abnormalities in schizophrenia

Epidemiologia e Psichiatria Sociale, 2010
AbstractThe magnetic resonance imaging studies investigating the volumes of the orbitofrontal cortex in patients suffering from schizophrenia are here presented, trying to elucidate its role for the pathophysiology and for the cognition of the disease.
Bellani, M, Cerruti, S, Brambilla, P
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The orbitofrontal cortex

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1996
The orbitofrontal cortex is the key brain region involved in emotion in humans and other primates. The orbitofrontal cortex represents the reward or affective value of primary reinforcers including taste, touch, texture, and face expression. It learns to associate other stimuli with these to produce representations of the expected reward value for ...
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The functions of the orbitofrontal cortex

Brain and Cognition, 1999
The orbitofrontal cortex contains the secondary taste cortex, in which the reward value of taste is represented. It also contains the secondary and tertiary olfactory cortical areas, in which information about the identity and also about the reward value of odours is represented.
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Sex, beauty and the orbitofrontal cortex

International Journal of Psychophysiology, 2007
Face perception is mediated by a distributed neural system in the human brain. Attention, memory and emotion modulate the neural activation evoked by faces, however the effects of gender and sexual orientation are currently unknown. To test whether subjects would respond more to their sexually-preferred faces, we scanned 40 hetero- and homosexual men ...
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The Orbitofrontal Cortex

2006
Abstract The orbitofrontal cortex (OFC) comprises the ventral surface of the frontal lobe, and is critical for functions ranging from olfaction and emotion to learning and behavioral flexibility. Since the time of Phineas Gage, this enigmatic brain region has intrigued clinicians due to its association with personality.
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Orbitofrontal cortex abnormality and deficit schizophrenia

Schizophrenia Research, 2013
Deficit syndrome, which is characterized by primary and enduring negative symptoms, is a homogeneous subtype within schizophrenia. Negative symptoms in schizophrenia are currently considered to be closely linked with frontal lobe impairment. However, the etiology in the frontal lobe of people with deficit syndrome is not fully understood.
Nobuhisa, Kanahara   +6 more
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Primate orbitofrontal cortex and adaptive behaviour

Trends in Cognitive Sciences, 2006
Orbitofrontal cortex contributes to behavioural adaptation in response to changes in the contingent relationship and incentive value of positive affective stimuli in the environment. This article integrates early descriptions of the effects of orbitofrontal ablation in monkeys, on object discrimination reversal and extinction, with contemporary ...
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The Orbitofrontal Cortex

2019
The book will be valuable for those in the fields of neuroscience, neurology, psychology, psychiatry, biology, animal behaviour, economics, and philosophy, from the undergraduate level upwards. The book is unique in providing a coherent multidisciplinary approach to understanding the functions of one of the most interesting regions of the human brain ...
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