Results 41 to 50 of about 7,373 (175)

Rituximab Treatment in a Patient with Active Graves’ Orbitopathy and Psoriasis

Türk Oftalmoloji Dergisi, 2017
Management of Graves’ orbitopathy remains an important therapeutic challenge. Current therapeutic modalities are unsatisfactory in about one third of patients.
Tülay Şimşek, Nilgün Yıldırım, Belgin Efe, Nur Kebapçı   +3 more
doaj   +1 more source

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei, Béla Kajtár, Tamás László, Hazem A Juratli, Livia Vida, Ágota Szepesi, Réka Mózes, Botond Timár, Jörg Halter, Stefan Dirnhofer, Alexandar Tzankov   +10 more
wiley   +1 more source

Clinical assessment of patients with Graves' orbitopathy [PDF]

Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2011
Clinical examination is the basis of a good assessment of a patient with Graves' orbitopathy. This study gives recommendations of the European orbitopathy group related to the activity and severity of the disease. The activity of the disease is estimated
Nedeljković-Beleslin Biljana
doaj   +1 more source

Drastic Response to Olaparib in a Patient With Metastatic Castration‐Resistant Prostate Cancer Harboring BRCA2 Alterations and Near‐Threshold Tumor Mutational Burden

IJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction BRCA2 alterations and high tumor mutational burden (TMB‐H) are responsible for prostate cancer; however, their co‐occurrence is uncommon, and evidence for PARP inhibition in the castration‐sensitive setting remains limited. We describe a case of metastatic castration‐resistant prostate cancer (CRPC) harboring both biomarkers ...
Kotaro Yokota, Takeo Kosaka, Tatsuaki Daimon, Shinnosuke Fujiwara, Kohei Nakamura, Hiroshi Nishihara, Mototsugu Oya   +6 more
wiley   +1 more source

Thyroid associated orbitopathy with ocular myasthenia in primary hypothyroidism: Keep those eyes open

Indian Journal of Endocrinology and Metabolism, 2013
Thyroid associated orbitopathy, although seen most commonly with thyrotoxicosis, is also known to occur in primary hypothyroidism. Myasthenia gravis is an autoimmune condition with an established association with autoimmune thyroid disease. We report the
Chitra Selvan, Deep Dutta, Indira Maisnam, Anubhav Thukral, P P Chakraborthy, Ajitesh Roy, Rakesh Arora, Soumik Dutta, Arjun Baidya, Sujoy Ghosh, Satinath Mukhopadhyay, Subhankar Chowdhury   +11 more
doaj   +1 more source

Consideration of specific key points improves outcome of decompression treatment in patients with endocrine orbitopathy: pre-/post-OP comparison and biomechanical simulation

European Journal of Medical Research, 2022
Endocrine orbitopathy is typically treated by resecting orbital walls. This procedure reduces intraorbital pressure by releasing intraorbital tissue, effectively alleviating the symptoms.
Matthias Krause, Michael-Tobias Neuhaus, Ina Sterker, Alexander K. Bartella, Annika Schönfeld, Bernd Lethaus, Rüdiger Zimmerer, Evgeny Gladilin   +7 more
doaj   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

Graves Orbitopathy [PDF]

Journal of Osteopathic Medicine, 2020
Stefano, Natali, Paul, Shogan
openaire   +2 more sources

The role of hormonal imbalance in the development of autoimmune dacryoadenitis in endocrine orbitopathy

Oftalʹmologiâ, 2014
The authors analyzed the hormonal profile of patients with Graves’ disease and endocrine orbitopathy with or without autoimmune dacryoadenitis.
V. G. Likhvantseva, T. N. Safonova, O. A. Gontyurova, E. A. Rudenko, V. A. Vygodin   +4 more
doaj   +3 more sources

A Mimicking Situation Of Active Disease In Thyroid Orbitopathy: The Use Of Topical Prostaglandin Analogs

Van Tıp Dergisi, 2017
Thyroid orbitopathy is an inflammatory and autoimmune disease of the orbital and periorbital tissues that characterized as developing autoantibodies against thyroid stimulating hormone receptor (TSH-R).
Aydın Yıldız
doaj   +1 more source