Results 91 to 100 of about 572,560 (281)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Dynamics of Black Hole Pairs II: Spherical Orbits and the Homoclinic Limit of Zoom-Whirliness

, 2008
Spinning black hole pairs exhibit a range of complicated dynamical behaviors. An interest in eccentric and zoom-whirl orbits has ironically inspired the focus of this paper: the constant radius orbits.
E. Ott, J. Levin, Janna Levin, R. Wald, Rebecca Grossman, T. Damour   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

New periodic orbits in the solar sail restricted three body problem [PDF]

, 2008
In this paper we consider periodic orbits of a solar sail in the Earth-Sun restricted three-body problem. In particular, we consider orbits which are high above the ecliptic plane, in contrast to the classical Halo orbits about the collinear equilibria ...
Biggs, J.D., McInnes, C., Waters, Thomas
core  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Stationary $D=4$ Black Holes in Supergravity: The Issue of Real Nilpotent Orbits

, 2016
The complete classification of the nilpotent orbits of ${\rm SO}(2,2)^2$ in the representation ${\bf (2,2,2,2)}$, achieved in \cite{Dietrich:2016ojx}, is applied to the study of multi-center, asymptotically flat, extremal black hole solutions to the STU ...
Andrianopoli, Andrianopoli, Andrianopoli, Andrianopoli, Astefanesei, Bates, Behrndt, Bellucci, Bena, Bergshoeff, Bertini, Borsten, Borsten, Borsten, Bossard, Bossard, Bossard, Bossard, Bossard, Breitenlohner, Brown, Chemissany, Chemissany, Chemissany, Chemissany, Chow, Chow, Clément, Collingwood, Cvetic, Cvetic, Cvetic, Cvetic, Dabholkar, Dall'Agata, de Boer, Deger, Denef, Dietrich, Djokovic, Ferrara, Ferrara, Ferrara, Ferrara, Ferrara, Ferrara, Fre, Fre, Fre, Gaillard, Gaiotto, Galli, Goldstein, Gunaydin, Gunaydin, Kim, Larsen, Levay, Lopes Cardoso, Pioline, Rasheed, Strominger, Vinberg, Virmani, Vân Lê   +64 more
core   +1 more source

Asteroids discovered in the Baldone Observatory between 2017 and 2022: The orbits of asteroid 428694 Saule and 330836 Orius

Open Astronomy
We discovered 83 asteroids at the Baldone Astrophysical Observatory (MPC code 069) in 2017–2022. We studied one of the dynamically interesting Apollo (Near Earth object) observed at the Baldone Astronomical Observatory, namely 428694 Saule (2008 OS9) and
Wlodarczyk Ireneusz, Černis Kazimieras, Eglitis Ilgmar   +2 more
doaj   +1 more source

Color Doppler imaging of the superior ophthalmic vein in patients with Graves' orbitopathy before and after treatment of congestive disease

Clinics, 2011
OBJECTIVE: To compare superior ophthalmic vein blood flow parameters measured with color Doppler imaging in patients with congestive Graves' orbitopathy before and after treatment and in normal controls.
Mário L. R. Monteiro, Rodrigo B. S. Moritz, Hélio Angotti Neto, Joseph E. Benabou   +3 more
doaj   +1 more source

Colour Doppler imaging of the orbital vasculature in Graves' disease with computed tomographic correlation [PDF]

, 2000
Mohan Rao K N
openalex   +1 more source