Results 91 to 100 of about 551,491 (329)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

HEOSAT: A mean elements orbit propagator program for Highly Elliptical Orbits

open access: yes, 2018
The algorithms used in the construction of a semi-analytical propagator for the long-term propagation of Highly Elliptical Orbits (HEO) are described. The software propagates mean elements and include the main gravitational and non-gravitational effects ...
Hautesserres, Denis   +2 more
core   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Analytic Central Orbits and their Transformation Group

open access: yes, 2008
A useful crude approximation for Abelian functions is developed and applied to orbits. The bound orbits in the power-law potentials A*r^{-alpha} take the simple form (l/r)^k = 1 + e cos(m*phi), where k = 2 - alpha > 0 and 'l' and 'e' are generalisations ...
Arnold   +21 more
core   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Can the integral curves of ODEs be accepted as orbits of an autonomous force field? [PDF]

open access: yesRendiconti di Matematica e delle Sue Applicazioni, 2009
It is shown that the two-parametric set of all solutions of any linear ordinary differential equation (ODE) of the second order y + a(x)y + b(x)y = f(x) (solvable by quadratures or not) can become a set of orbits traced by a material point of unit mass,
George Bozis, Francesco Borghero
doaj  

Chaotic orbits for spinning particles in Schwarzschild spacetime

open access: yes, 2010
We consider the orbits of particles with spin in the Schwarzschild spacetime. Using the Papapetrou-Dixon equations of motion for spinning particles, we solve for the orbits and focus on those that exhibit chaos using both Poincar\'e maps and Lyapunov ...
Hirschmann, Eric W., Verhaaren, Chris
core   +1 more source

Uncertainty quantification of thermal barrier coatings lifetime on rotating turbine blades considering chemo-thermo-mechanically coupling failure

open access: yesMaterials & Design
The lifetime prediction of thermal barrier coatings (TBCs) on rotating turbine blades remains a significant challenge due to the complex service environment and multi-physics failure mechanisms.
Weiliang Yan   +6 more
doaj  

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