Results 81 to 90 of about 112,180 (285)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The potentially hazardous NEA 2001 BB16
Open Astronomy, 2019 We computed the impact solutions of the potentially dangerous Near Earth Asteroid (NEA) 2001 BB16 based on 47 optical observations from January 20.08316 UTC, 2001, through February 09.15740 UTC, 2016, and one radar observation from January 19.90347 UTC ...
Wlodarczyk Ireneusz
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Orbits of the Asteroids Discovered at the Molėtai Observatory in 2000–2004
Open Astronomy, 2014 The paper presents statistics of the asteroids observed and discovered at the Molėtai Observatory, Lithuania in 2000–2004 within the project for astrometric observations of the near-Earth objects (NEOs), the main belt asteroids and comets.
Černis K. +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Symmetry, Integrability and Geometry: Methods and Applications, 2006 In the paper, properties of orbit functions are reviewed and further developed. Orbit functions on the Euclidean space E_n are symmetrized exponential functions.
Anatoliy Klimyk, Jiri Patera
doaj
Nuclear FusionA key challenge on the path towards burning plasmas is the measurement of the alpha particle phase space. Among the few experimental options available, gamma-ray spectroscopy (GRS) is a key method.
M. Nocente +18 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Erratum : “Closed orbits and tempered orbits” [PDF]
Annales scientifiques de l'École normale supérieure, 1990 Concerns the author's article reviewed above (especially proposition 4.2 and theorem 1.5).
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source