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Genome and evolution of Tibet orbivirus, TIBOV (genus Orbivirus, family Reoviridae) [PDF]

Frontiers in Cellular and Infection Microbiology
Tibet orbivirus (TIBOV) was first isolated from Anopheles maculatus mosquitoes in Xizang, China, in 2009. In recent years, more TIBOV strains have been isolated in several provinces across China, Japan, East Asia, and Nepal, South Asia.
Tingting Gao, Minghua Li, Hong Liu, Shihong Fu, Huanyu Wang, Guodong Liang   +5 more
doaj   +7 more sources

Characterization of a Novel Orbivirus from Cattle Reveals Active Circulation of a Previously Unknown and Pathogenic Orbivirus in Ruminants in Kenya [PDF]

mSphere, 2023
Arboviruses are among emerging pathogens of public and veterinary health significance. However, in most of sub-Saharan Africa, their role in the aetiologies of diseases in farm animals is poorly described due to paucity of active surveillance and ...
Dorcus C. A. Omoga, David P. Tchouassi, Marietjie Venter, Edwin O. Ogola, Solomon Langat, Caroline Getugi, Georg Eibner, Anne Kopp, Inga Slothouwer, Baldwyn Torto, Sandra Junglen, Rosemary Sang   +11 more
doaj   +7 more sources

A Novel Ephemero- and a New CHeRI Orbivirus Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) in Florida, USA [PDF]

Viruses
A novel ephemeral fever rhabdovirus and a CHeRI orbivirus of a previously unidentified genetic lineage were isolated in mosquito cell line C6/36 cells as co-infecting agents from the spleen tissue of a dead farmed white-tailed deer (WTD; Odocoileus ...
Emily DeRuyter, Pedro H. O. Viadanna, Kristen Wilson, Zoe White, Amira Richardson, Merrie Urban, Pacharapong Khrongsee, Thais C. S. Rodrigues, Thomas B. Waltzek, Juan M. Campos Krauer, Samantha M. Wisely, Kuttichantran Subramaniam, John A. Lednicky   +12 more
doaj   +4 more sources

Whole-Genome Sequencing and Structure Study of Three Biting-Insect-Associated Viruses (<i>Yunnan Orbivirus</i>, Guangxi Orbivirus, and Yongshan Totivirus) Isolated in Yunnan, China. [PDF]

Adv Virol
Yunnan Province is an area in China with a major prevalence of biting arthropods (including mosquitos, ticks, and Culicoides) and arboviruses including dengue virus (DENV), bluetongue virus (BTV), and epizootic hemorrhagic disease virus (EHDV). Therefore,
Li Z, Duan Y, Zhu J, Li L.
europepmc   +4 more sources

Discovery and Characterization of Bukakata orbivirus (Reoviridae:Orbivirus), a Novel Virus from a Ugandan Bat [PDF]

Viruses, 2019
While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized.
Anna C. Fagre, Justin S. Lee, Robert M. Kityo, Nicholas A. Bergren, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Luke Nyakarahuka, Amy T. Gilbert, Julian Kerbis Peterhans, Mary B. Crabtree, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Amy J. Schuh, Stuart T. Nichol, Julius J. Lutwama, Barry R. Miller, Rebekah C. Kading   +18 more
doaj   +7 more sources

First Isolation and Molecular Characterization of Umatilla Virus (Sedoreoviridae, Orbivirus) in Brazil. [PDF]

Viruses
In this study, we provide a genomic description of the first isolation of the Umattila virus (UMAV) in Brazil. The virus was obtained from the blood of a bird (Turdus fumigatus) and isolated in a C6/36 cell culture. The viral genome contains ten segments,
Barros L, Silva S, Cruz AC, da Silva E, Wanzeller AL, Carvalho V, Chiang J, Martins L.   +7 more
europepmc   +6 more sources

Evaluation of vector susceptibility in Aedes aegypti and Culex pipiens pallens to Tibet orbivirus [PDF]

mSphere
Mosquito-borne viruses cause various infectious diseases in humans and animals. Tibet orbivirus (TIBOV), a newly identified arbovirus, efficiently replicates in different types of vertebrate and mosquito cells, with its neutralizing antibodies detected ...
Nanjie Ren, Qianqian Jin, Fei Wang, Doudou Huang, Cihan Yang, Wahid Zaman, Ferdinand Villanueva Salazar, Qiyong Liu, Zhiming Yuan, Han Xia   +9 more
doaj   +4 more sources

Orbivirus NS4 Proteins Play Multiple Roles to Dampen Cellular Responses [PDF]

Viruses, 2023
Non-structural protein 4 (NS4) of insect-borne and tick-borne orbiviruses is encoded by genome segment 9, from a secondary open reading frame. Though a protein dispensable for bluetongue virus (BTV) replication, it has been shown to counter the ...
Fauziah Mohd Jaafar, Mourad Belhouchet, Baptiste Monsion, Lesley Bell-Sakyi, Peter P. C. Mertens, Houssam Attoui   +5 more
doaj   +3 more sources

Double-stranded RNA orbivirus disrupts the DNA-sensing cGAS-sting axis to prevent type I IFN induction. [PDF]

Cell Mol Life Sci
Cyclic GMP-AMP synthase (cGAS) is a DNA sensing cellular receptor that induces IFN-I transcription in response to pathogen and host derived cytosolic DNA and can limit the replication of some RNA viruses.
Louloudes-Lázaro A, Nogales-Altozano P, Rojas JM, Veloz J, Carlón AB, Van Rijn PA, Martín V, Fernández-Sesma A, Sevilla N.   +8 more
europepmc   +3 more sources

Dwarf bat’s (Pipistrellus pipistrellus) lung diploid cell strains and their permissivity to orbiviruses (Reoviridae: Orbivirus) – pathogens of vector-borne animal diseases

Вопросы вирусологии, 2022
Introduction. Bat cell cultures are a popular model both for the isolation of vector-borne disease viruses and for assessing the possible role of these mammalian species in forming the natural reservoirs of arbovirus infection vectors. The goal of the
Olga S. Povolyaeva, Anna A. Chadaeva, Andrey V. Lunitsin, Sergey G. Yurkov   +3 more
doaj   +4 more sources