Characterization of a Novel Orbivirus from Cattle Reveals Active Circulation of a Previously Unknown and Pathogenic Orbivirus in Ruminants in Kenya [PDF]
mSphere, 2023 The genus Orbivirus contains several viruses that cause large outbreaks in wild and domestic animals. However, there is little knowledge on the contribution of orbiviruses to diseases in livestock in Africa.
Dorcus C. A. Omoga +11 more
doaj +8 more sources
A Novel Ephemero- and a New CHeRI Orbivirus Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) in Florida, USA [PDF]
VirusesA novel ephemeral fever rhabdovirus and a CHeRI orbivirus of a previously unidentified genetic lineage were isolated in mosquito cell line C6/36 cells as co-infecting agents from the spleen tissue of a dead farmed white-tailed deer (WTD; Odocoileus ...
Emily DeRuyter +12 more
doaj +4 more sources
Evaluation of vector susceptibility in Aedes aegypti and Culex pipiens pallens to Tibet orbivirus [PDF]
mSphereMosquito-borne viruses cause various infectious diseases in humans and animals. Tibet orbivirus (TIBOV), a newly identified arbovirus, efficiently replicates in different types of vertebrate and mosquito cells, with its neutralizing antibodies detected ...
Nanjie Ren +9 more
doaj +4 more sources
Discovery and Characterization of Bukakata orbivirus (Reoviridae:Orbivirus), a Novel Virus from a Ugandan Bat [PDF]
Viruses, 2019 While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized. We describe a novel orbivirus (Reoviridae:Orbivirus) isolated from an Egyptian fruit bat (Rousettus aegyptiacus leachii) trapped in 2013 in Uganda and named Bukakata ...
Anna Fagre +18 more
doaj +8 more sources
First Isolation and Molecular Characterization of Umatilla Virus (Sedoreoviridae, Orbivirus) in Brazil [PDF]
VirusesIn this study, we provide a genomic description of the first isolation of the Umattila virus (UMAV) in Brazil. The virus was obtained from the blood of a bird (Turdus fumigatus) and isolated in a C6/36 cell culture. The viral genome contains ten segments, and its organization is characteristic of viruses of the genus Orbivirus (family Sedoreoviridae ...
Landeson Barros +7 more
europepmc +6 more sources
Identification of Orbivirus Non-Structural Protein 5 (NS5), Its Role and Interaction with RNA/DNA in Infected Cells. [PDF]
Int J Mol Sci, 2023 Bioinformatic analyses have predicted that orbiviruses encode an additional, small non-structural protein (NS5) from a secondary open reading frame on genome segment 10.
Mohd Jaafar F +3 more
europepmc +4 more sources
Orbivirus NS4 Proteins Play Multiple Roles to Dampen Cellular Responses [PDF]
Viruses, 2023 Non-structural protein 4 (NS4) of insect-borne and tick-borne orbiviruses is encoded by genome segment 9, from a secondary open reading frame. Though a protein dispensable for bluetongue virus (BTV) replication, it has been shown to counter the ...
Fauziah Mohd Jaafar +5 more
doaj +3 more sources
Double-stranded RNA orbivirus disrupts the DNA-sensing cGAS-sting axis to prevent type I IFN induction. [PDF]
Cell Mol Life SciCyclic GMP-AMP synthase (cGAS) is a DNA sensing cellular receptor that induces IFN-I transcription in response to pathogen and host derived cytosolic DNA and can limit the replication of some RNA viruses.
Louloudes-Lázaro A +8 more
europepmc +3 more sources
Вопросы вирусологии, 2022 Introduction. Bat cell cultures are a popular model both for the isolation of vector-borne disease viruses and for assessing the possible role of these mammalian species in forming the natural reservoirs of arbovirus infection vectors. The goal of the
Olga S. Povolyaeva +3 more
doaj +4 more sources
Confusions in orbivirus protein classification [PDF]
Virology Journal, 2012 An extensive comparative analysis of orbivirus genomes revealed four cases of unclear numeration and protein designation, due to confused reference to protein size or segment size by which they are encoded. A concise nomenclature based on type species, sequence homology and functional characteristics independent of segment or protein size is suggested.
Dilcher, Meik, Weidmann, Manfred
doaj +9 more sources