Results 101 to 110 of about 42,436 (244)

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Causal associations of MICB, CTSA, and MMP9 proteins with oral cancer: Mendelian randomization study

Scientific Reports
Oral cancer (ORCA) is the most prevalent histological subtype of oral malignancies in which immune modulation is relevant. The goal of this work was to employ Mendelian randomization (MR) to investigate the causal connection between the immune-related ...
Bowen Dong, Jianlei Hua, Shengxuan Ma, Li Wang, Haotian Xiao, Xianghe Qiao, Rui Zhao, Yiming Liu   +7 more
doaj   +1 more source

Wild Orca [PDF]

, 2019
In the San Juan Islands of the Pacific Northwest, hundreds of people gather each year to listen and sing with pods of orcas. Wild Orca takes this real life event and puts it in the perspective of young Mia.
Hall, Megan
core  

The ORCA quantum chemistry program package

, 2020
In this contribution to the special software-centered issue, the ORCA program package is described. We start with a short historical perspective of how the project began and go on to discuss its current feature set.
Ute Becker, Wennmohs, F., Becker, U., Neese, F., Riplinger, C., Christoph Riplinger, Frank Wennmohs, Frank Neese   +7 more
core   +1 more source

Pediatric Human Olfactory Epithelium Mirrors Adult Structure and Function in a Human Olfactory Organoid Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Objective This study investigated the developmental differences in structure, gene expression, and function of human olfactory epithelium (OE) using pediatric and adult specimens and human olfactory organoids. Background Olfactory dysfunction (OD) is characterized by loss or alterations in the sense of smell and has an age‐related increase in ...
Randy Bach, Ankit Chauhan, Michael Xiang, Kang‐Hoon Kim, James N. Palmer, Nithin D. Adappa, Michael A. Kohanski, Noam A. Cohen, Hong Wang, Jennifer E. Douglas   +9 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Orca hydrofoil shape optimization using Bezier curve and artificial neural network – multiple objective genetic algorithm for low flow velocity

Journal of King Saud University: Engineering Sciences
Tidal energy is a clean and predictable power source commonly harnessed using horizontal-axis tidal turbines. The power generation process of these turbines is influenced by various elements, including the hydrofoil performance metrics such as the lift ...
Muhammad Ihsan Masykur, Harinaldi
doaj   +1 more source

Der Teil und das Ganze: Feldabhängige THz‐ESR‐Spektroskopie sondiert gitterabhängige elektronische Struktur beim Spin‐Crossover von Eisen(II)

Angewandte Chemie, EarlyView.
Die THz‐ESR‐Spektroskopie ermöglicht einen direkten Zugang zur energetisch niedrig liegenden elektronischen Struktur und zur Spin‐Phonon‐Kopplung in Spin‐Crossover‐(SCO)‐Komplexen des Eisen(II). Die Quantifizierung des High‐Spin‐Anteils (γHS) und subtile Verschiebungen magnetischer Übergänge offenbaren den Einfluss des umgebenden Gitters und ...
Jooris Beyer, Gerald Ebert, Andreas Dürrmann, Benjamin Kintzel, Gerald Hörner, Tarek Al Said, Karsten Holldack, Birgit Weber, Winfried Plass   +8 more
wiley   +1 more source

ORCA Annual Report 2025-26

Quick Facts about ORCA in Academic Year 2025-26 30 slots filled for Posters-at-the-Capitol 443+ students presented at Scholars Weeks with support from 126+ faculty members 53 grants awarded Dr.
ORCA, MSU
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Orca

, 2004
Distributed by Chip Taylor Communications, 2 East View Drive, Derry, NH 03038-4812; 800-876-CHIP (2447)Produced by Filmoption InternationalDirected by Pierre D’Amour2003, VHS, color, 52 min.
Barbara Butler
core   +1 more source