Orchestrating Embodied Systems through the Embodied Context Protocol: Motivation, Progress, and Directions. [PDF]
Ma F +7 more
europepmc +1 more source
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Enhancing the Resilience of ROS 2-Based Multi-Robot Systems with Kubernetes: A Case Study on UWB-Based Relative Positioning. [PDF]
Zhang J, Yu X, Westerlund T.
europepmc +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
From the logic of coordination to goal-directed reasoning: the agentic turn in artificial intelligence. [PDF]
Haidemariam T.
europepmc +1 more source
Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang +10 more
wiley +1 more source
Context-Aware Multi-Agent Architecture for Wildfire Insights. [PDF]
Sandeep A +5 more
europepmc +1 more source
Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai +15 more
wiley +1 more source
The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley +1 more source
MCP-enabled LLM for meta-optics inverse design: leveraging differentiable solver without LLM expertise. [PDF]
Huang Y +7 more
europepmc +1 more source

