Results 171 to 180 of about 56,843 (293)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Lightweight Container Orchestration for Reproducible AI and Deep Learning Segmentation of Coronary Arteries and the Aorta in Coronary CT Angiography. [PDF]

Diagnostics (Basel)
Iwanski M, Regulski P, Wendykier P.
europepmc   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Agentic AI-enhanced digital twins for Smart City civil infrastructure: A secure, autonomous and auditable management framework. [PDF]

PLoS One
Syed TA, Akarma A, Alatify A, Naqash MT, Alqurashi A.   +4 more
europepmc   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Agentic systems in computational pathology: architectures, evidence, and translational challenges. [PDF]

J Transl Med
Lu X, Li Q, Gao Y, Dong W, Lyu M, Ma S, Li J, Wu Y, Cai L, Zhang T, Lyu S, Liu Z, Liu H, Luo S.   +13 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

From Biomedical Datasets to Fairness-Aware Recommendations: An Integrated Data Orchestration Pipeline for Binary Clinical Predictions. [PDF]

Comput Struct Biotechnol J
Alberola M, Copado P, Vellido A, König C.   +3 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Dorsal raphe tau pathology disrupts sleep-wake orchestration and sleep architecture in a sex-specific manner. [PDF]

Alzheimers Dement
Kolling LJ, Wang R, Gaudencio GS, Fishbeyn JS, James TD, Mason SM, McCoy RO, Song Z, McConnell IP, Ziemke K, Janik KM, Xu Y, Bierlein-De La Rosa G, Ismail S, Marcinkiewcz CA.   +14 more
europepmc   +1 more source