Results 41 to 50 of about 128,939 (270)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Weaving aspects into web service orchestrations [PDF]
, 2005 Web Service orchestration engines need to be more open to enable the addition of new behaviours into service-based applications. In this paper, we illus- trate how, in a BPEL engine with aspect-weaving ca- pabilities, a process-driven application ...
Courbis, C., Finkelstein, A.
core +2 more sources
Engineering Proceedings, 2023 The methodology basic principles of the neuro-evolutionary synthesis of multi-object multi-criteria systems control models under conflict and uncertainty in real time are discussed.
Vladimir A. Serov +3 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Resilient Critical Infrastructure Management using Service Oriented Architecture [PDF]
, 2009 —The SERSCIS project aims to support the use of interconnected systems of services in Critical Infrastructure (CI) applications. The problem of system interconnectedness is aptly demonstrated by ‘Airport Collaborative Decision Making’ (ACDM).
Hall-May, Martin, Surridge, Mike
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Deploying elastic routing capability in an SDN/NFV-enabled environment [PDF]
, 2015 SDN and NFV are two paradigms that introduce unseen flexibility in telecom networks. Where previously telecom services were provided by dedicated hardware and associated (vendor-specific) protocols, SDN enables to control telecom networks through ...
Colle, Didier +6 more
core +1 more source
Proactive and Intelligent Monitoring and Orchestration of Cloud-Native IP Multimedia Subsystem
IEEE Open Journal of the Communications SocietyAs the cloud moves from monolithic infrastructure to a self-isolated cloud native microservice environment, automation is becoming an important aspect for the management of the application life cycle.
Rasel Chowdhury +3 more
doaj +1 more source
ClusVNFI: A Hierarchical Clustering-Based Approach for Solving VNFI Dilemma in NFV Orchestration
IEEE Access, 2019 Network functions virtualization (NFV) is becoming a prevailing design for future Internet by migrating network functions from dedicated hardware appliances to software instances running in virtual computing platforms.
Jing Chen +3 more
doaj +1 more source
Recent Advances in Data Engineering for Networking
IEEE Access, 2022 This tutorial paper examines recent advances in data engineering, focusing on aspects of network management and orchestration. We provide a comprehensive analysis of standardization efforts as well as platform development activities related to data ...
Engin Zeydan, Josep Mangues-Bafalluy
doaj +1 more source