Results 41 to 50 of about 129,157 (271)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Neuro-Evolutionary Synthesis of Game Models of Control under Uncertainty Based on Distributed Computing Technology

open access: yesEngineering Proceedings, 2023
The methodology basic principles of the neuro-evolutionary synthesis of multi-object multi-criteria systems control models under conflict and uncertainty in real time are discussed.
Vladimir A. Serov   +3 more
doaj   +1 more source

Orchestration of semantic web services in IRS-III [PDF]

open access: yes, 2004
In this paper we describe our orchestration model for IRS-III. IRS-III is a framework and platform for developing WSMO based semantic web services. Orchestration specifies how a complex web service calls subordinate web services.
Confalonieri, Roberto   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Resilient Critical Infrastructure Management using Service Oriented Architecture [PDF]

open access: yes, 2009
—The SERSCIS project aims to support the use of interconnected systems of services in Critical Infrastructure (CI) applications. The problem of system interconnectedness is aptly demonstrated by ‘Airport Collaborative Decision Making’ (ACDM).
Hall-May, Martin, Surridge, Mike
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Proactive and Intelligent Monitoring and Orchestration of Cloud-Native IP Multimedia Subsystem

open access: yesIEEE Open Journal of the Communications Society
As the cloud moves from monolithic infrastructure to a self-isolated cloud native microservice environment, automation is becoming an important aspect for the management of the application life cycle.
Rasel Chowdhury   +3 more
doaj   +1 more source

ClusVNFI: A Hierarchical Clustering-Based Approach for Solving VNFI Dilemma in NFV Orchestration

open access: yesIEEE Access, 2019
Network functions virtualization (NFV) is becoming a prevailing design for future Internet by migrating network functions from dedicated hardware appliances to software instances running in virtual computing platforms.
Jing Chen   +3 more
doaj   +1 more source

Recent Advances in Data Engineering for Networking

open access: yesIEEE Access, 2022
This tutorial paper examines recent advances in data engineering, focusing on aspects of network management and orchestration. We provide a comprehensive analysis of standardization efforts as well as platform development activities related to data ...
Engin Zeydan, Josep Mangues-Bafalluy
doaj   +1 more source

End-to-end 5G service deployment and orchestration in optical networks with QoE guarantees [PDF]

open access: yes, 2018
© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new ...
Agraz Bujan, Fernando   +3 more
core   +1 more source

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