Results 51 to 60 of about 59,128 (285)

Orchestration as a Means of the Synthesis of Classical and Romantic Approaches in Brahms’ Second Piano Concerto

open access: yesMuzikološki Zbornik, 2021
The synthesis of ‘Classical’ and ‘Romantic’ concepts in the orchestration of Brahms’ Second Piano Concerto is discussed. The composer rethinks ways of presenting musical material in the orchestra by conceptualising both the ‘Classical’ orchestral ...
Vadim Rakochi
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Towards Secure Cloud Orchestration for Multi-Cloud Deployments [PDF]

open access: yes, 2018
Cloud orchestration frameworks are commonly used to deploy and operate cloud infrastructure. Their role spans both vertically (deployment on infrastructure, platform, application and microservice levels) and horizontally (deployments from many distinct ...
Dang, H., Paladi, N., Michalas, A.
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Proactive and Intelligent Monitoring and Orchestration of Cloud-Native IP Multimedia Subsystem

open access: yesIEEE Open Journal of the Communications Society
As the cloud moves from monolithic infrastructure to a self-isolated cloud native microservice environment, automation is becoming an important aspect for the management of the application life cycle.
Rasel Chowdhury   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

ChemOS 2.0: an orchestration architecture for chemical self-driving laboratories [PDF]

open access: yes, 2023
Self-driving laboratories (SDLs), which combine automated experimental hardware with computational experiment planning, have emerged as powerful tools for accelerating materials discovery. The intrinsic complexity created by their multitude of components
Alán, Aspuru-Guzik   +7 more
core   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Automated Debugging Mechanisms for Orchestrated Cloud Infrastructures With Active Control and Global Evaluation

open access: yesIEEE Access
Orchestration methods at Infrastructure-as-a-Service (IaaS) level automate the deployment, scaling, and management of virtualized resources, typically across multiple hosts and data centres.
Jozsef Kovacs   +2 more
doaj   +1 more source

Grid service orchestration using the Business Process Execution Language (BPEL) [PDF]

open access: yes, 2005
Modern scientific applications often need to be distributed across grids. Increasingly applications rely on services, such as job submission, data transfer or data portal services. We refer to such services as grid services.
Chen, L.   +4 more
core  

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