Results 71 to 80 of about 56,843 (293)

Orchestrating Communities, Ubiquities, Time and Space: International Experiences in the Use of Educational Technology

open access: yesQualitative Research in Education, 2014
In this brief introduction we frame the special issue on “Orchestrating communities, ubicuity, time and space: International experiences in the use of educational technology.“ It constitutes the result of the “International experiences in the use of ...
Iván M. Jorrín-Abellán   +1 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Online Parallelized Service Function Chain Orchestration in Data Center Networks

open access: yesIEEE Access, 2019
In recent years, much attention has been focused on deploying service function chains (SFCs), each of which is composed of a set of virtual network functions (VNFs) in a specified order.
Gang Sun   +4 more
doaj   +1 more source

Zum Verhältnis von Harmonik und Instrumentation ›vor Wagner‹ [PDF]

open access: yesZeitschrift der Gesellschaft für Musiktheorie, 2014
Bereits in Kompositionen aus der Mitte des 18. Jahrhunderts lassen sich Akkorde finden, deren harmonische Funktionen nicht allein durch Merkmale begründet werden, die in den Bereich tonaler Kategorien fallen (wie Akkordtyp, Stufenrelation, Beziehung auf ...
Michael Polth
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evolution strategy of 5G network based on cloud-native computing

open access: yesDianxin kexue, 2018
Cloud-native computing which is from IT domain covers a range of paths and methods that apply to different industries and also meet the needs of business diversity.Based on the 5G service-based architecture,advantages and challenges of introducing cloud ...
Jian SU
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Distributed Awareness for Class Orchestration [PDF]

open access: yes
The orchestration process consists of managing classroom interactions at multiple levels: individual activities, teamwork and class-wide sessions. We study the process of orchestration in recitation sections, i.e.
Alavi, Hamed   +2 more
core   +2 more sources

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