Results 81 to 90 of about 59,128 (285)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Orchestration at the edge reduces network latency
, 2022 : Edge computing brings benefits to users by reducing network latency, thus improving services, but needs management orchestration. Here, we demonstrate how orchestration improves latency in an automotive edge-computing use case by reallocating network ...
Marquez-Barja, Johann +1 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
ETRI JournalFunction-as-a-Service (FaaS) applications suffer from cold-start latency owing to their high execution time and memory usage. We propose a FaaS orchestra-tion framework based on a cloud-agnostic approach for application and data interoperability.
Zameer Ahmed Adhoni +1 more
doaj +1 more source
Network Slicing for Customizing 5G Networks for Industry-Specific Needs [PDF]
Iranian Journal of Information Processing & ManagementBackground: Network slicing has turned out to be one of the key enablers in the 5G networks due to the ability to support the diverse applications such as ultra reliable and low latency communications for the self-driving cars or IoT-like massive machine
Mustafa M. Zayer +4 more
doaj +1 more source
Lightweight Coordination Patterns for Applications of the Internet of Things
Applied Computer Systems, 2020 Applications of the Internet of Things (IoT) are famously known for connecting devices via the internet. The main purpose of IoT systems (wireless or wired) is to connect devices together for data collection, buffering and data gateway.
Mufti Waseem Akhtar
doaj +1 more source
, 2012 We define game orchestration as the activity of creating experiences for game players at run-time. This paper presents a design space for game orchestration techniques, and describes two novel game orchestration systems ...
Bellay, Quentin +7 more
core +1 more source
Towards a fully automated and optimized network security functions orchestration [PDF]
, 2019 cloud computing;computer network management;computer network security;software defined networking;virtualisation;Network Functions Virtualization;Software-Defined Networking;network management;Security Automation approach;automatic management tools;cloud
Fulvio Valenza +5 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source