Results 51 to 60 of about 129,157 (271)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

IMPROVING THE EFFICIENCY OF MASTERING DISTRIBUTED INFORMATION SYSTEMS IN A VIRTUAL COMPUTER LAB BASED ON THE USE OF CONTAINERIZATION AND CONTAINER ORCHESTRATION TECHNOLOGIES

Современные информационные технологии и IT-образование, 2018
This article discusses issues surrounding the training of specialists in distributed information systems using innovative methods and technologies in a virtual computer lab environment with an integrated knowledge management system.
Mikhail A. Belov, Yuri A. Kryukov, Maksim А. Mikheev, Pavel E. Lupanov, Nadezhda А. Tokareva, Evgenia N. Cheremisina   +5 more
doaj   +1 more source

Federated Networks for Distributed Analysis of Health Data

Frontiers in Public Health, 2021
Access to health data, important for population health planning, basic and clinical research and health industry utilization, remains problematic. Legislation intended to improve access to personal data across national borders has proven to be a double ...
Harry Hallock, Serena Elizabeth Marshall, Peter A. C. 't Hoen, Jan F. Nygård, Bert Hoorne, Cameron Fox, Sharmini Alagaratnam   +6 more
doaj   +1 more source

Weaving aspects into web service orchestrations [PDF]

, 2005
Web Service orchestration engines need to be more open to enable the addition of new behaviours into service-based applications. In this paper, we illus- trate how, in a BPEL engine with aspect-weaving ca- pabilities, a process-driven application ...
Courbis, C., Finkelstein, A.
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Automated Debugging Mechanisms for Orchestrated Cloud Infrastructures With Active Control and Global Evaluation

IEEE Access
Orchestration methods at Infrastructure-as-a-Service (IaaS) level automate the deployment, scaling, and management of virtualized resources, typically across multiple hosts and data centres.
Jozsef Kovacs, Bence Ligetfalvi, Robert Lovas   +2 more
doaj   +1 more source

FORGOTTEN PAGES FROM ION MACOVEI’S CREATION [PDF]

Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2015
This article is devoted to Ion Macovei’s creation, namely, to his Symphonieta Florile dalbe (lily-whiteflowers) in the ver­sion for string orchestra, realized by conductor Dumitru Goia.
COCEAROVA GALINA
doaj  

Enabling the Orchestration of IoT Slices through Edge and Cloud Microservice Platforms

Sensors, 2019
This article addresses one of the main challenges related to the practical deployment of Internet of Things (IoT) solutions: the coordinated operation of entities at different infrastructures to support the automated orchestration of end-to-end Internet ...
Juan-Manuel Fernandez, Ivan Vidal, Francisco Valera   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Assessing the level of maturity of a territory's innovation ecosystem: methodological foundations and tools

π-Economy
Models for assessing the level of digital maturity are widely used as a tool for justifying decisions on the development of organizations. Similar models exist in the field of assessing the maturity of ecosystems.
Gileva Tatiana
doaj   +1 more source