Results 31 to 40 of about 12,909 (204)

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Electrocardiographic Repolarization Changes Following Orchiectomy: Insights Into QT Interval Prolongation and Clinical Implications

Annals of Noninvasive Electrocardiology
Introduction Sex steroid hormones influence ventricular repolarization and QT interval duration. Testosterone has been associated with shorter QT intervals, whereas androgen deprivation may prolong repolarization indices.
Yuta Sakaguchi, Kenichi Iijima, Naomasa Suzuki, Takahiro Hakamata, Yasuhiro Ikami, Sou Otsuki, Nobue Yagihara, Daisuke Izumi, Takayuki Inomata   +8 more
doaj   +1 more source

Guidance for shared decision-making regarding orchiectomy in individuals with differences of sex development due to 17-β-hydroxysteroid dehydrogenase type 3 deficiency

Frontiers in Pediatrics
17β-hydroxysteroid dehydrogenase type 3 deficiency is a 46,XY difference of sex development (DSD) that may present in childhood with inguinal testes or at puberty following virilization. We present four individuals, assigned female at birth, to highlight
Lissa X. Yu, Jodie Johnson, Christine M. Pennesi, Christine M. Pennesi, Michelle M. Ernst, Michelle M. Ernst, Andrew Strine, Andrew Strine, Armand H. Matheny Antommaria, Armand H. Matheny Antommaria, Robert J. Hopkin, Robert J. Hopkin, David E. Sandberg, Behzad Khorashad, Lauren Mohnach, Amer Heider, Meilan M. Rutter, Meilan M. Rutter   +17 more
doaj   +1 more source

A Case of Paratesticular Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma

Journal of Urological Surgery, 2015
A very rare case of paratesticular atypical lipomatous tumor/a case of welldifferentiated liposarcoma diagnosed in an elderly patient is presented together with macroscopic surgical photographs and photographs of microscopic pathological sections.
Hikmet Köseoğlu, Kutsal Yörükoğlu
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Prepubertal Testicular Tumors in Children: Single Center 17 Years Experience

Journal of Pediatric Research, 2023
Aim:Testicular tumors are rare in children and have a bimodal distribution. The first peak is at two years of age in boys and comprises mainly non-GCNIS derived tumors (pre-pubertal teratoma and yolk sac lesions).
Muhammed Hamidullah Çakmak, Serdar Moralıoğlu, Ayşenur Celayir   +2 more
doaj   +1 more source

Sex Cord-Stromal Tumors of Testis: A Clinicopathologic and Follow-Up Study of 15 Cases in a High-Volume Institute of China

Frontiers in Medicine, 2022
ObjectivesTo report the first series of testicular sex cord-stromal tumors (TSCSTs) with detailed clinicopathologic findings and long-term follow-up in the Chinese population.Patients and MethodsFrom 2008 to 2018, 15 patients with TSCST were included in ...
Yin Huang, Yin Huang, Bo Chen, Dehong Cao, Zeyu Chen, Jin Li, Jianbing Guo, Qiang Dong, Qiang Wei, Liangren Liu   +9 more
doaj   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Ultrasound-Guided Funicular Block: Ropivacaine Injection into the Tissue around the Spermatic Cord to Improve Analgesia during Orchiectomy in Dogs

Animals, 2021
Orchiectomy is a common surgical procedure performed on small animals, and it requires postoperative pain management despite its relative simplicity.
Vincenzo Cicirelli, Pasquale Debidda, Nicola Maggio, Michele Caira, Giovanni M. Lacalandra, Giulio G. Aiudi   +5 more
doaj   +1 more source