Results 41 to 50 of about 18,392 (244)

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Giant primary retroperitoneal seminoma: A case report [PDF]

Vojnosanitetski Pregled, 2016
Introduction. Primary extragonadal seminomas are rare tumors. There have been only a few cases of the primary retroperitoneal seminomas reported in the literature up to date. Case report.
Jovanović Milan, Janjušević Nataša, Mirković Darko, Vulović Maja, Milev Boško, Mitrović Miroslav, Trifunović Bratislav   +6 more
doaj   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Pathologic and Oncologic Outcomes of Patients Undergoing Orchiectomy After Chemotherapy for Advanced Testicular Germ Cell Tumors

European Urology Open Science
Background and objective: Delayed orchiectomy is generally recommended for patients who receive upfront chemotherapy for advanced testicular germ cell tumors (TGCTs).
Viranda H. Jayalath, Fady Baky, Samuel A. Gold, Nicole Liso, Brandon Williams, Samuel A. Funt, Darren R. Feldman, Victor E. Reuter, Joel Sheinfeld, Richard S. Matulewicz   +9 more
doaj   +1 more source

Morphofunctional and Metabolic Alterations after Orchiectomy

, 2016
Objective: To verify alterations in lipid profile, blood glucose and pressure, and morphological aspects of the adrenal gland in animals with hypogonadism secondary to total bilateral epididymectomy and orchiectomy.Methods: Young and adult male Wistar ...
Diego Paim Carvalho Garcia, Denny Fabrício Magalhães Veloso, Andy Petroianu, Leonardo De Souza Vasconcellos, Luiz Ronaldo Alberti   +4 more
core   +1 more source

Bilateral orchiectomy deteriorates the structure and function of seminal vesicles in a rat model [PDF]

, 2023
© 2023, The Author(s), under exclusive licence to Springer Nature Limited.The effects of hormone levels on ejaculation are known. In addition to thyroid hormone levels, testosterone levels are also associated with ejaculation, but no consensus has been ...
Durmus, Nergiz, Sarac, Ayberk, Ongun, Sakir, ESEN, AHMET ADİL, Guner, Ozge, Sarikaya, Ege, SEL, EDA KÜBRA, Demir, Omer, Sel, Eda, Eda Sel, Ege Sarikaya, Ayberk Sarac, Omer Demir, Nergiz Durmus, Ahmet Adil Esen, Ozge Guner, Sakir Ongun   +16 more
core   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Guidance for shared decision-making regarding orchiectomy in individuals with differences of sex development due to 17-β-hydroxysteroid dehydrogenase type 3 deficiency

Frontiers in Pediatrics
17β-hydroxysteroid dehydrogenase type 3 deficiency is a 46,XY difference of sex development (DSD) that may present in childhood with inguinal testes or at puberty following virilization. We present four individuals, assigned female at birth, to highlight
Lissa X. Yu, Jodie Johnson, Christine M. Pennesi, Christine M. Pennesi, Michelle M. Ernst, Michelle M. Ernst, Andrew Strine, Andrew Strine, Armand H. Matheny Antommaria, Armand H. Matheny Antommaria, Robert J. Hopkin, Robert J. Hopkin, David E. Sandberg, Behzad Khorashad, Lauren Mohnach, Amer Heider, Meilan M. Rutter, Meilan M. Rutter   +17 more
doaj   +1 more source

A Case of Paratesticular Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma

Journal of Urological Surgery, 2015
A very rare case of paratesticular atypical lipomatous tumor/a case of welldifferentiated liposarcoma diagnosed in an elderly patient is presented together with macroscopic surgical photographs and photographs of microscopic pathological sections.
Hikmet Köseoğlu, Kutsal Yörükoğlu
doaj   +1 more source

The effects of orchiectomy and steroid on fertility in experimental testicular atrophy [PDF]

, 2023
PMID: 37258102WOS:001007406100004Objective: Despite our understanding of Sertoli cell function and the state of spermatogenesis, the underlying mechanisms remain unclear.
Kocabaş, Rahim, Kozacioglu, Sumeyye, Yurtcu, Müslim, Kozacıoğlu, Sümeyye   +3 more
core   +1 more source