Results 81 to 90 of about 24,628,666 (285)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
INFLUENCE OF THE "TIME DEFICIENCY" STRESS ON THE THYROID STATUS AND INDICES OF STRESS RESPONSE
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019 Background. Currently, the most urgent stressor is time deficiency (TD), which causes the development of emotional stress (S). The aim of the research was to study the influence of the «time deficiency» stress on the severity of parameters that ...
Gusakova E. A., Gorodetskaya I. V.
doaj +1 more source
Higher-Order Discrimination [PDF]
, 1990 This discussion treats a set of familiar social derelictions as consequences of the perversion of a universalistic moral theory in the service of an ill-considered or insufficiently examined personal agenda.The set includes racism, sexism, anti-Semitism,
Piper, Adrian M. S.
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Ordered chaining for total orderings [PDF]
, 1994 We design new inference systems for total orderings by applying rewrite techniques to chaining calculi. Equality relations may either be specified axiomatically or built into the deductive calculus via paramodulation or superposition. We demonstrate that our inference systems are compatible with a concept of (global) redundancy for clauses and ...
Bachmair, L., Ganzinger, H.
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
On Degrees in the Hasse Diagram of the Strong Bruhat Order
, 2006 For a permutation $\pi$ in the symmetric group $S_n$ let the {\it total degree} be its valency in the Hasse diagram of the strong Bruhat order on $S_n$, and let the {\it down degree} be the number of permutations which are covered by $\pi$ in the strong ...
Ron M. Adin +4 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Bulletin of the Royal College of Surgeons of EnglandEmbracing the College values.
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source