Results 31 to 40 of about 1,436,716 (264)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Customer order scheduling in a permutation flow shop environment
Operations Research PerspectivesVarious recent scheduling literature has studied the so called customer order scheduling problem. In this class of scheduling problems, there are multiple customer orders, and each of them consists of several jobs.
Julius Hoffmann +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Second order chiral kinetic theory under gravity and antiparallel charge-energy flow
Journal of High Energy Physics, 2021 We derive the chiral kinetic theory under the presence of a gravitational Riemann curvature. It is well-known that in the chiral kinetic theory there inevitably appears a redundant ambiguous vector corresponding to the choice of the Lorentz frame.
Tomoya Hayata +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Utility of high-order scheme for unsteady flow simulations: Comparison with second-order tool
Journal of Ocean Engineering and ScienceThe objective of this work is to investigate the utility and effectiveness of the high-order scheme for simulating unsteady turbulent flows. To achieve it, the studies are conducted from two perspectives: (i) the ability of different numerical schemes to
Peng Jiang +4 more
doaj +1 more source
Controllability of Flow-Conservation Transportation Networks with Fractional-Order Dynamics
Complexity, 2021 In this paper, we adapt the fractional derivative approach to formulate the flow-conservation transportation networks, which consider the propagation dynamics and the users’ behaviors in terms of route choices.
Wei Chen, Bo Zhou
doaj +1 more source
Propulsion and Power Research, 2021 This communication reports, the flow of viscoelastic nanofluid with third order slip flow condition, Cattaneo-Christov heat and mass diffusion model. The joined non-linear ordinary differential equations (ODEs) were acquired from the partial differential
Wubshet Ibrahim +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Fourth Order Energy Dissipative Scheme for a Traffic Flow Model
Mathematics, 2020 We propose, analyze and numerically validate a new energy dissipative scheme for the Ginzburg–Landau equation by using the invariant energy quadratization approach.
Xiaowei Chen, Mingzhan Song, Songhe Song
doaj +1 more source