Results 111 to 120 of about 2,173,914 (285)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Biermann interpolation of Birkhoff type

open access: yesJournal of Numerical Analysis and Approximation Theory, 2005
If \(P_{0},P_{1},...,P_{r}\) and \(Q_{0},Q_{1},...,Q_{r}\) are Birkhoff univariate projectors which form the chains\[P_{0}\le P_{1}\le\dots\le P_{r},\quad Q_{0}\le Q_{1}\le\dots\le Q_{r},\]we can define the Biermann operator of Birkhoff type\[B_{r}^{B ...
Marius Birou
doaj   +2 more sources

Local approximation of DSGE models around the risky steady state [PDF]

open access: yes
A DSGE model takes the mathematical form of a system of nonlinear stochastic equations. Except in a very few cases, there is no analytical solution and economists are left using numerical methods in order to obtain approximated solutions.
Juillard Michel
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Approximation of derivatives by nonlinear operators

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
Two theorems on simultaneous approximation are obtained by using generalized convex operators.
Radu Păltănea
doaj   +2 more sources

Dynamic Analysis of Planar 3-RRR Flexible Parallel Robots with Dynamic Stiffening

open access: yesShock and Vibration, 2014
In consideration of the second-order coupling quantity of the axial displacement caused by the transverse displacement of flexible beam, the first-order approximation coupling model of planar 3-RRR flexible parallel robots is presented, in which the ...
Qinghua Zhang, Xuerui Fan, Xianmin Zhang
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Approximate Solutions to Games of Ordered Preference

open access: yes2025 IEEE 28th International Conference on Intelligent Transportation Systems (ITSC)
Autonomous vehicles must balance ranked objectives, such as minimizing travel time, ensuring safety, and coordinating with traffic. Games of ordered preference effectively model these interactions but become computationally intractable as the time horizon, number of players, or number of preference levels increase.
Pau de las Heras Molins   +5 more
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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