Results 81 to 90 of about 166,385,429 (248)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Certificate of Incorporation of the Order of the First Families of Virginia, 1607-1620

open access: yes, 1913
Includes a copy of the certificate of incorporation of the Order of the First Families of Virginia dated May 7, 1913. Also contains signed statement by George M.
Order of the First Families of Virginia, 1607-1620
core  

The approximation of second-order miniterm approximation acoustic wave equation via homotopy analysis method

open access: yes四川大学学报. 自然科学版, 2016
Due to the complexity of sound waves in the atmosphere, the numerical simulation method is widely applied, but the expressions of the analytical solution are not given, and its precision is limited.
JI Juan-Juan   +3 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Justification of the Cauchy-Born approximation of elastodynamics [PDF]

open access: yes, 2013
We present sharp convergence results for the Cauchy-Born approximation of general classical atomistic interactions, for static problems with small data and for dynamic problems on a macroscopic time ...
Ortner, Christoph, Theil, Florian
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Local approximation of DSGE models around the risky steady state [PDF]

open access: yes
A DSGE model takes the mathematical form of a system of nonlinear stochastic equations. Except in a very few cases, there is no analytical solution and economists are left using numerical methods in order to obtain approximated solutions.
Juillard Michel
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

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