Results 61 to 70 of about 4,349,562 (266)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

On Gaussian Quadra Fibona-Pell Sequence and A Quaternion Sequence Formed by the Terms of This Sequence

Düzce Üniversitesi Bilim ve Teknoloji Dergisi
In this study, the Gaussian quadra Fibona-Pell sequence is proposed and examined. The quadra Fibona-Pell sequence is first extended to define the Gaussian quadra Fibona-Pell sequence.
Arzu Özkoç Öztürk, Faruk Kaplan
doaj   +1 more source

Two Fibonacci-like sequences [PDF]

Notes on Number Theory and Discrete Mathematics
In the present paper we will discuss the two Fibonacci-like sequences s₂ₖ₊₁=s₂ₖ-s₂ₖ₋₁+...-s₁+s₀ with s₀=a₀,...,s₂ₖ=a₂ₖ and s₂ₖ₊₂=s₂ₖ₊₁-s₂ₖ+...+s₁-s₀ with s₀=a₀,...,s₂ₖ=a₂ₖ₊₁, where a₀,...,a₂ₖ₊₁ are arbitrary numbers.
Krassimir T. Atanassov, Anthony G. Shannon   +1 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

A Recurrence Relation Approach to Higher Order Quantum Superintegrability

Symmetry, Integrability and Geometry: Methods and Applications, 2011
We develop our method to prove quantum superintegrability of an integrable 2D system, based on recurrence relations obeyed by the eigenfunctions of the system with respect to separable coordinates.
Ernie G. Kalnins, Jonathan M. Kress, Willard Miller Jr.   +2 more
doaj   +1 more source

On fourth-order jacobsthal quaternions

Journal of Mathematical Sciences and Modelling, 2018
In this paper, we present for the first time a sequence of quaternions of order 4 that we will call the fourth-order Jacobsthal and the fourth-order Jacobsthal-Lucas quaternions. In particular, we are interested in the generating function, Binet formula,
Gamaliel Cerda-morales
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Non-orientable surface-plus-one-relation groups

, 2011
Recently Dicks–Linnell determined the L2-Betti numbers of the orientable surface-plus-one-relation groups, and their arguments involved some results that were obtained topologically by Hempel and Howie.
Antolin, Yago, Dicks, Warren, Linnell, Peter A.   +2 more
core   +1 more source