Results 51 to 60 of about 4,349,562 (266)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Metaphysical Order. Suárez’s Theory of Real Relation

open access: yesDoctor Virtualis
È cosa nota che la nozione di relazione sia uno dei pilastri teorici della dottrina metafisica e della teologia di molti autori Scolastici medievali e moderni e sia alla base della loro visione cosmologica del mondo. Questo saggio intende ricostruire la
Nicola Milanesi
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Well quasi-order in combinatorics : embeddings and homomorphisms

open access: yes, 2015
The notion of well quasi-order (wqo) from the theory of ordered sets often arises naturally in contexts where one deals with infinite collections of structures which can somehow be compared, and it then represents a useful discriminator between ‘tame ...
Ruskuc, Nik   +3 more
core   +1 more source

A Relation-Based Page Rank Algorithm for Semantic Web Search Engines [PDF]

open access: yes, 2009
With the tremendous growth of information available to end users through the Web, search engines come to play ever a more critical role. Nevertheless, because of their general-purpose approach, it is always less uncommon that obtained result sets provide
Sanna, Andrea   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Novel Charge Ordering in the Trimer Iridium Oxide BaIrO3

open access: yesCrystals, 2016
We have prepared polycrystalline samples of the trimer Ir oxide BaIrO3 with face-shared Ir3O12 trimers, and have investigated the origin of the phase transition at 182 K by measuring resistivity, thermopower, magnetization and synchrotron X-ray ...
Ichiro Terasaki   +10 more
doaj   +1 more source

Higher-Order Hamiltonian for Circuits with (α,β) Elements

open access: yesEntropy, 2020
The paper studies the construction of the Hamiltonian for circuits built from the (α,β) elements of Chua’s periodic table. It starts from the Lagrange function, whose existence is limited to Σ-circuits, i.e., circuits built exclusively from elements ...
Zdeněk Biolek   +3 more
doaj   +1 more source

Institutional Design of the Order 220 in Relation to Digital and Classical Markets

open access: yesСовременная конкуренция, 2023
The proposed article reflects a methodological description and specific proposals for the content of certain provisions of the Procedure for analyzing the state of competition in the commodity market, approved in accordance with Order No.
Irina V. Knyazeva
doaj   +1 more source

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