Results 81 to 90 of about 1,409,700 (267)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Mobile Food Ordering Application using Android OS Platform
EPJ Web of Conferences, 2014 The purpose of this research is making an ordering food application based on Android with New Order, Order History, Restaurant Profile, Order Status, Tracking Order, and Setting Profile features.
Ricky Michael Yosep
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Systems of Fundamental Units in Cubic Orders
Journal of Number Theory, 1995 \textit{H. J. Stender} found infinitely many irreducible polynomials \(\varphi (X) = X^3 + eX^2 + fX + g\) of \(\mathbb{Z} [X]\) having three real roots and involving two (resp. three) parameters such that \(\{\lambda + r,\;\lambda + s\}\) (resp. \(\{(\lambda + kr)/ \lambda,\;(\lambda + ks)/ \lambda\})\) is a fundamental system of units of \(\mathbb{Z}
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Journal of Industrial Engineering and Operation ManagementEfisiensi dalam mengelola persediaan sangat penting bagi kelangsungan bisnis. Jumlah barang yang disimpan secara berlebihan akan menaikkan ongkos penyimpanan, sementara persediaan yang tidak mencukupi dapat mengakibatkan kekurangan produk. dan mengganggu
Putri Aulia Angelina +2 more
doaj +1 more source
Journal of Statistical Software, 2013 In many applications one may be interested in drawing inferences regarding the order of a collection of points on a unit circle. Due to the underlying geometry of the circle standard constrained inference procedures developed for Euclidean space data are
Sandra Barragán +3 more
doaj +1 more source
On Buekenhout-Metz unitals of even order
European Journal of Combinatorics, 1992 A unital is a \(2-(n^ 3+1,n+1,1)\) design. The classical example of a unital is the set of absolute points in a projective plane \(\text{PG}(2,n^ 2)\) with respect to a unitary polarity, blocks being the sets of points on secant lines. A class of unitals, including the classical ones, can be constructed inside \(\text{PG}(2,n^ 2)\) by a method due to ...
openaire +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source