Results 71 to 80 of about 1,409,700 (267)

A unital in the hughes plane of order nine

open access: yesDiscrete Mathematics, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Unital designs in planes of order 16

open access: yesDiscrete Applied Mathematics, 2000
A unital is any \(2\)-\((q^3 + 1, q + 1, 1)\) design. The classical example of a unital is an Hermitian curve embedded in \(\text{PG}(2, q^2)\). It should be noted that not all unitals of order \(q\) are embedded in projective planes of order \(q^2\).
Stoicho D. Stoichev, Vladimir D. Tonchev
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

ORDER ISOMORPHISMS OF COMPLETE ORDER-UNIT SPACES

open access: yesCanadian Journal of Mathematics
We investigate order isomorphisms, which are not assumed to be linear, between complete order unit spaces. We show that two such spaces are order isomorphic if and only if they are linearly order isomorphic. We then introduce a condition which determines whether all order isomorphisms on a complete order unit space are automatically affine.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modified Current Differencing Unit and its Application for Electronically Reconfigurable Simple First-order Transfer Function

open access: yesAdvances in Electrical and Computer Engineering, 2015
Modified current differencing unit (MCDU) and its simple filtering application are introduced in this paper. Modification of the well-known current differencing unit consists in weighted difference of both input currents controlled by adjustable ...
SOTNER, R.   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Decision rules for robotic mobile fulfillment systems

open access: yesOperations Research Perspectives, 2019
The Robotic Mobile Fulfillment Systems (RMFS) is a new type of robotized, parts-to-picker material handling system, designed especially for e-commerce warehouses.
M. Merschformann   +3 more
doaj   +1 more source

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