Results 61 to 70 of about 1,563,954 (315)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Oscillation of arbitrary-order derivatives of solutions to linear differential equations taking small functions in the unit disc

Electronic Journal of Differential Equations, 2015
In this article, we study the relationship between solutions and their derivatives of the differential equation $$ f''+A(z)f'+B(z)f=F(z), $$ where $A(z), B(z), F(z)$ are meromorphic functions of finite iterated p-order in the unit disc.
Pan Gong, Li-Peng Xiao
doaj  

The Role of Health Institutions in Training Healthcare Personnel for the Digital Transition: The International Training Program of the Order of Physicians and Dentists of Rome

International Medical Education
Digital health, encompassing the use of digital technologies in healthcare, and telemedicine, facilitating healthcare delivery across long distances, have witnessed widespread applications across various healthcare domains.
Maria Chiara Gatto, Emanuela Maria Frisicale, Pietro Palopoli, Martina Sapienza, Emanuele Caroppo, Cristina Patrizi, Giovanni Migliano, Gianfranco Damiani   +7 more
doaj   +1 more source

A unital in the hughes plane of order nine

Discrete Mathematics, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Proper and Unit Trapezoid Orders and Graphs

Order, 1998
We show that the class of trapezoid orders in which no trapezoid strictly contains any other trapezoid strictly contains the class of trapezoid orders in which every trapezoid can be drawn with unit area. This is different from the case of interval orders, where the class of proper interval orders is exactly the same as the class of unit interval ...
Bogart, Kenneth P., Möhring, Rolf H., Ryan, Stephen P.   +2 more
openaire   +3 more sources

Testing for cointegration using induced-order statistics [PDF]

, 2008
Unit root tests, Cointegration tests, Nonlinearity, Robustness, Induced order statistics, Engle and Granger test,
Alvaro Escribano, Santos, T., Sipols, Ana E., M. Santos, Escribano, Álvaro, Ana Sipols   +5 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

On Buekenhout-Metz unitals of odd order

Journal of Combinatorial Theory, Series A, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ronald D. Baker, Gary L. Ebert
openaire   +2 more sources

An unconditional maximum likelihood test for a unit root [PDF]

, 1993
We investigate a test for unit roots in autoregressive time series based on maximization of the unconditional likelihood. This is the likelihood function appropriate for stationary time series.
González-Farias, Graciela, Dickey, David A.   +1 more
core