Results 71 to 80 of about 230,507 (313)
Double field theory at order α′ [PDF]
Journal of High Energy Physics, 2014 We investigate $α'$ corrections of bosonic strings in the framework of double field theory. The previously introduced "doubled $α'$-geometry" gives $α'$-deformed gauge transformations arising in the Green-Schwarz anomaly cancellation mechanism but does not apply to bosonic strings.
Hohm, Olaf, Zwiebach, Barton
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Achieving large electric-field-induced strain in lead-free piezoelectrics
Materials Research Letters, 2019 Lead-free piezoelectric single crystals of Fe-doped 0.95(Bi1/2Na1/2)TiO3-0.05BaTiO3 are shown to combine multiple mechanisms for high strain and an effective piezoelectric coefficient of up to 3260 pm/V.
Patrick Tung +6 more
doaj +1 more source
Ordered array structures for efficient perovskite solar cells
Engineering Reports, 2020 In the past few years, metal halide perovskite solar cells (PSCs) have attracted widespread attention in the photovoltaic field, and their power conversion efficiency has rapidly exceeded 25%.
Fengren Cao +4 more
doaj +1 more source
Boson Fields in Ordered Magnets
Acta Physica Polonica A, 2015 Spin wave theory of magnetism reveals two severe shortcomings. First, it considers non quantized classical spins and, second, the predicted temperature power functions for the thermal decrease of the magnetic order parameter hold asymptotically at T = 0 only.
Hoser, A., Köbler, U.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2006 Ion channels are one of the main drug targets and are in the focus of various membrane biosensor applications and drug screening assays. The aim of this thesis was to develop and characterize a novel membrane system suspending highly ordered porous ...
Römer, Winfried
core +1 more source
The Astrophysical JournalThe afterglows of gamma-ray bursts are nonthermal electron synchrotron emissions from relativistic shocks. The origin of strong magnetic field in the emission region remains elusive, and two field amplification mechanisms via the plasma kinetic and ...
Asuka Kuwata +3 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source