Results 101 to 110 of about 10,799,493 (290)

On the intermediate value theorem over a non-Archimedean field

open access: yesLe Matematiche, 2013
The paper investigates general properties of the power series over a non- Archimedean ordered field, extending to the set of algebraic power series the intermediate value theorem and Rolle's theorem and proving that  an algebraic series attains its ...
Luigi Corgnier   +2 more
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Orders in quadratic fields, III

open access: yesProceedings of the Japan Academy, Series A, Mathematical Sciences, 1994
The results in this paper continue the parts I and II with the same title [cf. ibid. 69, No. 3, 45-48 (1993; Zbl 0795.11056) and the author and \textit{L.-C. Zhang}, ibid., No. 9, 368-371 (1993; see the preceding review)]. Namely, the author first disproves a conjecture posed in part I concerning a criterion for the ideal class group of complex ...
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Evidence of sp-d Exchange Interactions in CdSe Nanocrystals Doped with Mn, Fe and Co: Atomistic Tight-Binding Simulation

open access: yesNanomaterials
Exploiting the atomistic tight-binding theory with the sp-d exchange term, the electronic and magnetic characteristics of CdSe nanoparticles embedded with Mn, Fe and Co are determined as a function of external magnetic fields to realize the sp-d exchange
Pruet Kalasuwan, Worasak Sukkabot
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Irreducible many-body correlations in topologically ordered systems

open access: yesNew Journal of Physics, 2016
Topologically ordered systems exhibit large-scale correlation in their ground states, which may be characterized by quantities such as topological entanglement entropy.
Yang Liu, Bei Zeng, D L Zhou
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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