Results 81 to 90 of about 94,120 (308)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Ordered fields and metrizability

open access: yes, 2009
application/pdf論文(Article)We recall that an ordered field is a field which has a linear order and the order topology (by this order). Order fields have played important roles in the theory of the real number field R in terms of Archimedes axiom or the ...
TANAKA,Yoshio
core  

The Skolem–Bang theorems in ordered fields with an IP

open access: yes, 2008
This paper is concerned with the extent to which the Skolem–Bang theorems in Diophantine approximations generalize from the standard setting of 〈R,Z〉 to structures of the form 〈F,I〉, where F is an ordered field and I is an integer part of F. We show that
Ayat, Seyed Masih, Seyed Masih Ayat
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Approximation Properties for Orderings on ∗ -Fields [PDF]

open access: yesTransactions of the American Mathematical Society, 1988
The goal of this paper is to extend the main theorems on approximation properties of the topological space of orderings from formally real fields to skew fields with an involution
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Semiclassical projective planes over half-ordered fields [PDF]

open access: yes, 1995
T his paper concerns a generalization of Moulton planes constructed by J. Jakóbowski [2]. We consider those planes over ordered fields and solve the isomorphism and collineation problem posed in [2]
Steinke, Günter F.
core  

Time-integrated Polarization of Structured Jets in Gamma-Ray Burst Prompt Emission

open access: yesThe Astrophysical Journal
The structure of gamma-ray burst (GRB) jets remains one of the most significant open questions in high-energy astrophysics. Observations of events like GRB 170817A, associated with gravitational waves, and the exceptionally bright GRB 221009A suggest ...
Qiannan Mai   +7 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Computability theory, reverse mathematics, and ordered fields

open access: yes, 2009
The effective content of ordered fields is investigated using tools of computability theory and reverse mathematics. Computable ordered fields are constructed with various interesting computability theoretic properties. These include a computable ordered
Levin, Oscar Louis
core  

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