Results 131 to 140 of about 321,441 (313)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Some 𝑙-simple pathological lattice-ordered groups
, 1976 The purpose of this note is to explore two recently discovered lattice-ordered groups, and to establish that they are l l -simple, i.e., have no proper l l -ideals. These groups are “pathologically o
A. M. W. Glass, Stephen H. McCleary
core +1 more source
Two-dimensional shape memory graphene oxide
Nature Communications, 2016 When reducing the size of shape memory materials to the nanoscale regime, the memory effect tends to diminish. Here, the authors report a theoretical proposal of a shape memory graphene oxide with ordered epoxy groups retaining excellent programmability ...
Zhenyue Chang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
$\sigma$-interpolation lattice-ordered groups
, 2000 summary:In [1], Jakubík showed that the class of $\sigma $-interpolation lattice-ordered groups forms a radical class, but left open the question of whether the class forms a torsion class.
Darnel, Michael R.
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Archimedean Closed Lattice-Ordered Groups [PDF]
, 2004 We show that, if an abelian lattice-ordered group is archimedean closed, then each principal l-ideal is also archimedean closed. This has given a positive answer to the question raised in 1965 and hence proved that the class of abelian archimedean closed
Conrad, Paul +2 more
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source