Results 141 to 150 of about 1,425,221 (328)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Closure operators on radical classes of lattice-ordered groups [PDF]
, 1987 Michael R. Darnel
openalex +1 more source
Designs for phase I trials in ordered groups. [PDF]
Stat Med, 2017 Conaway MR, Wages NA.
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A design for phase I trials in completely or partially ordered groups. [PDF]
Stat Med, 2017 Conaway MR.
europepmc +1 more source
Amalgamating abelian ordered groups [PDF]
Pacific Journal of Mathematics, 1972 openaire +3 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A classification of finite rank dimension groups by their representations in ordered real vector spaces [PDF]
, 2010 Gregory R. Maloney, Aaron Tikuisis
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Simplicial geometry of unital lattice-ordered abelian groups [PDF]
, 2013 Leonardo Manuel Cabrer
openalex +1 more source