Results 61 to 70 of about 3,042,978 (240)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Complexity of Datalog on Linear Orders
, 2009 We study the program complexity of datalog on both finite and infinite linear orders. Our main result states that on all linear orders with at least two elements, the nonemptiness problem for datalog is EXPTIME-complete.
Grohe, Martin, Schwandtner, Goetz
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Analysis of the experience of pedagogical support of military personnel in a military university
Вестник Северо-Кавказского федерального университетаIntroduction. The relevance of the study is due to the results of the analysis, which allow characterizing the existing experience of pedagogical support for military personnel.Goal.
O. O. Nazarenko +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Regularities and Irregularities in Order Flow Data
, 2017 We identify and analyze statistical regularities and irregularities in the recent order flow of different NASDAQ stocks, focusing on the positions where orders are placed in the orderbook.
Guhr, Thomas +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Definition of basic and supporting parts of Alfa foils, a.s. planning system [PDF]
Acta Montanistica Slovaca, 2008 Aggregate planning cummulates into one target capacity, materials, economy and technology rules with aim to minimizesubjective approaches at the production plan designing and utilization of automatic (pseudoexpert) system for making productionplanning ...
Zuzana Marková +2 more
doaj
Ultrafilter extensions of linear orders [PDF]
, 2013 It was recently shown that arbitrary first-order models canonically extend to models (of the same language) consisting of ultrafilters. The main precursor of this construction was the extension of semigroups to semigroups of ultrafilters, a technique ...
Saveliev, Denis I.
core