Results 81 to 90 of about 36,652 (259)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
N-FRACTIONAL CALCULUS OPERATOR METHOD TO THE EULER EQUATION
Проблемы анализа, 2018 We can obtain the explicit solutions of the Euler equation by using the fractional calculus methods. So, we apply the N operator method in the fractional calculus to solve this equation in this paper.
R. Yilmazer, O. Ozturk
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Complex-Valued Ordinary Differential Equation Modeling for Time Series Identification
IEEE Access, 2019 Time series identification is one of the key approaches to dealing with time series data and discovering the change rules. Therefore, time series forecasting can be treated as one of the most challenging issues in this field.
Bin Yang, Wenzheng Bao
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
On the solution of some simple fractional differential equations
International Journal of Mathematics and Mathematical Sciences, 1990 The differintegration or fractional derivative of complex order ν, is a generalization of the ordinary concept of derivative of order n, from positive integer ν=n to complex values of ν, including also, for ν=−n a negative integer, the ordinary n-th ...
L. M. B. C. Campos
doaj +1 more source
Modified Riccati technique for half-linear differential equations with delay
Electronic Journal of Qualitative Theory of Differential Equations, 2014 We study the half-linear differential equation $$ (r(t)\Phi(x'(t)))'+c(t)\Phi(x(\tau(t)))=0,\quad \Phi(x):=|x|^{p-2}x,\ p>1. $$ We formulate new oscillation criteria for this equation by comparing it with a certain ordinary linear or half-linear ...
Simona Fišnarová, Robert Marik
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source