Results 101 to 110 of about 138,809 (284)

Operational Solution of Non-Integer Ordinary and Evolution-Type Partial Differential Equations

open access: yesAxioms, 2016
A method for the solution of linear differential equations (DE) of non-integer order and of partial differential equations (PDE) by means of inverse differential operators is proposed.
Konstantin V. Zhukovsky   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

The Fucik spectra for multi-point boundary-value problems

open access: yesElectronic Journal of Differential Equations, 2010
We study the structure of the Fucik spectra for the linear multi-point differential operators. We introduce a variational approach in order to obtain a robust and global algorithm which is suitable for the exploration of unknown Fucik spectrum ...
Gabriela Holubova, Petr Necesal
doaj  

Spectrality of ordinary differential operators

open access: yes, 2004
AmsLaTeX, 26 pages, added section on dissipative operators and ...
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Existence of periodic traveling wave solutions to the generalized forced Boussinesq equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1999
The generalized forced Boussinesq equation, utt−uxx+[f(u)]xx+uxxxx=h0, and its periodic traveling wave solutions are considered. Using the transform z=x−ωt, the equation is converted to a nonlinear ordinary differential equation with periodic boundary ...
Kenneth L. Jones, Yunkai Chen
doaj   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Commutative Algebras of Ordinary Differential Operators with Matrix Coefficients

open access: yes, 1996
A classification of commutative integral domains consisting of ordinary differential operators with matrix coefficients is established in terms of morphisms between algebraic curves.Comment: AMS-TeX format, 16 ...
Kimura, Masato, Mulase, Motohico
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

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