Results 51 to 60 of about 328,940 (311)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spectral Collocation Method for Fractional Differential/Integral Equations with Generalized Fractional Operator

open access: yesInternational Journal of Differential Equations, 2019
Generalized fractional operators are generalization of the Riemann-Liouville and Caputo fractional derivatives, which include Erdélyi-Kober and Hadamard operators as their special cases.
Qinwu Xu, Zhoushun Zheng
doaj   +1 more source

Quantum curves

open access: yes, 2014
One says that a pair (P,Q) of ordinary differential operators specify a quantum curve if [P,Q]=const. If a pair of difference operators (K,L) obey the relation KL=const LK we say that they specify a discrete quantum curve. This terminology is prompted by
Schwarz, Albert
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On weighted positivity of ordinary differential operators

open access: yesJournal of Inequalities and Applications, 1999
Some elliptic differential operators possess a weighted positivity property, where the weight is a fundamental solution of the operator. This property has interesting applications to partial differential operators.
Eilertsen Stefan
doaj  

Constructive factorization of LPDO in two variables

open access: yes, 2005
We study conditions under which a partial differential operator of arbitrary order $n$ in two variables or ordinary linear differential operator admits a factorization with a first-order factor on the left.
A. Loewy   +8 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Nonpoint Symmetry and Reduction of Nonlinear Evolution and Wave Type Equations

open access: yesAbstract and Applied Analysis, 2015
We study the symmetry reduction of nonlinear partial differential equations with two independent variables. We propose new ansätze reducing nonlinear evolution equations to system of ordinary differential equations.
Ivan Tsyfra, Tomasz Czyżycki
doaj   +1 more source

Raising and Lowering operators of spin-weighted spheroidal harmonics

open access: yes, 2016
In this paper we generalize the spin-raising and lowering operators of spin-weighted spherical harmonics to linear-in-$\gamma$ spin-weighted spheroidal harmonics where $\gamma$ is an additional parameter present in the second order ordinary differential ...
Shah, Abhay G., Whiting, Bernard F.
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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