Evaluation of the Variability of the ORF34, ORF68, and MLST Genes in EHV-1 from South Korea [PDF]
Pathogens, 2021 Equine herpesvirus-1 (EHV-1) is an important pathogen in horses. It affects horses worldwide and causes substantial economic losses. In this study, for the first time, we characterized EHV-1 isolates from South Korea at the molecular level. We then aimed
Hyung-Woo Kang +11 more
doaj +5 more sources
Equid alphaherpesvirus 1 from Italian Horses: Evaluation of the Variability of the ORF30, ORF33, ORF34 and ORF68 Genes [PDF]
Viruses, 2019 Equid alphaherpesvirus 1 (EHV-1) is an important pathogen of horses. It is spread worldwide and causes significant economic losses. The ORF33 gene has a conserved region that is often used as target in diagnostic PCR protocols.
Silvia Preziuso +3 more
doaj +5 more sources
A pentameric protein ring with novel architecture is required for herpesviral packaging [PDF]
eLife, 2021 Genome packaging in large double-stranded DNA viruses requires a powerful molecular motor to force the viral genome into nascent capsids, which involves essential accessory factors that are poorly understood.
Allison L Didychuk +5 more
doaj +2 more sources
Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene [PDF]
Molecular Systems BiologyComplex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Despite viral genomes being smaller and more gene dense than their hosts, we generally lack a sense of scope for the features governing the ...
David W Morgens +5 more
doaj +2 more sources
Outbreak of equid herpesvirus 1 abortions at the Arabian stud in Poland [PDF]
BMC Veterinary Research, 2020 Background Equid herpesvirus 1 (EHV-1) infections are endemic worldwide, including Poland. Many are subclinical, but some are associated with respiratory disease, abortion, neonatal foal death, or neurological disease.
Karol Stasiak +2 more
doaj +2 more sources
First identification and isolation of equine herpesvirus type 1 in aborted fetal lung tissues of donkeys [PDF]
Virology JournalBackground Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys. Results This was the first survey-based study of Chinese donkeys.
Panpan Tong +11 more
doaj +2 more sources
Kaposi's Sarcoma-Associated Herpesvirus ORF68 Is a DNA Binding Protein Required for Viral Genome Cleavage and Packaging. [PDF]
J Virol, 2018 Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma and several B-cell cancers, causing significant morbidity and mortality in immunocompromised individuals. A critical step in the production of infectious viral progeny is the packaging of the newly replicated viral DNA genome into the capsid ...
Gardner MR, Glaunsinger BA.
europepmc +6 more sources
Molecular Characterisation of Equine Herpesvirus 1 Isolates from Cases of Abortion, Respiratory and Neurological Disease in Ireland between 1990 and 2017 [PDF]
Pathogens, 2019 Multiple locus typing based on sequencing heterologous regions in 26 open reading frames (ORFs) of equine herpesvirus 1 (EHV-1) strains Ab4 and V592 was used to characterise 272 EHV-1 isolates from 238 outbreaks of abortion, respiratory or neurological ...
Marie Garvey +5 more
doaj +2 more sources
Molecular characterisation of equid alphaherpesvirus 1 strains isolated from aborted fetuses in Poland [PDF]
Virology Journal, 2018 Background Equid alphaherpesvirus 1 (EHV-1) is one of the main infectious causative agents of abortion in mares and can also be associated with stillbirth, neonatal foal death, rhinopneumonitis in young horses and a neurological disorder called equine ...
Anna Karolina Matczuk +3 more
doaj +2 more sources
Viruses, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), one of the most prevalent cancers of people living with HIV/AIDS in sub-Saharan Africa.
Yasaman Mortazavi +5 more
doaj +1 more source