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Conservation and variation in orf virus genomes
Virology, 1987The genomes of several orf virus strains were analyzed with the restriction endonucleases EcoRI, HindIII, BamHI, and KpnI, and cleavage site maps were deduced. In general, the right half of the genome showed conservation of restriction sites compared with the left half.
A J, Robinson +4 more
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Orf virus infection in sheep or goats
Veterinary Microbiology, 2015Orf virus, a member of the genus Parapoxvirus, is the causative agent of contagious ecthyma ('Orf'). It is a pathogen with worldwide distribution, causing significant financial losses in livestock production. The disease mainly affects sheep and goats, but various other ruminants and mammals have been reported to be infected as well.
V, Spyrou, G, Valiakos
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Orf virus: A promising new therapeutic agent
Reviews in Medical Virology, 2018SummaryThe orf virus (ORFV) is a zoonotic, epitheliotropic, DNA parapoxvirus that infects principally sheep and goats. Exposure of animals to the virus or immunization by an ORFV preparation can accentuate the severity of disease, which has provoked an interest in the underlying cellular, virological, and molecular mechanisms.
Ruixue Wang +3 more
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Orf virus infection and host immunity
Current Opinion in Infectious Diseases, 2006A summary of recent advances in our knowledge of the biology of orf virus is presented to illustrate the interaction of a zoonotic pathogen with host skin. This is providing novel and interesting data on the viral mechanism of skin infection and the host response.The full genome sequences of two parapoxviruses (orf virus and bovine papular stomatitis ...
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Orf virus and vaccinia virus do not cross-protect sheep
Archives of Virology, 1988Inoculation of lambs with a New Zealand strain of orf virus (NZ 2) failed to protect them against subsequent infection with the Lister strain of vaccinia virus. Similarly, in the reciprocal test, vaccinia virus failed to protect against subsequent orf virus infection. Inoculation with either orf virus or vaccinia virus alone afforded protection against
A J, Robinson, A A, Mercer
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Virucidal efficacy of common disinfectants against orf virus
Veterinary Record, 2010ORF virus (OV) infections are present in countries worldwide, and have a considerable economic impact on the agricultural sector. OV infections are regarded as one of the most important diseases affecting the welfare of farmed animals.
GALLINA, LAURA, SCAGLIARINI, ALESSANDRA
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Natural transmission of orf virus from clinically normal ewes to orf‐naive sheep
Veterinary Record, 1996The apparent natural transmission of orf virus from clinically normal ewes to susceptible sheep was observed during a border disease vaccine experiment. The 14 susceptible sheep were persistently infected with border disease virus and had been reared indoors in isolation from other sheep since birth.
P F, Nettleton +4 more
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The structure and cloning of orf virus DNA
Virology, 1987A map of cleavage sites for the restriction endonucleases EcoRI, HindIII, BamHI, HpaI, and KpnI for a New Zealand strain of orf virus (NZ2) DNA has been deduced. Also, the entire genome, apart from approximately 0.1 kbp at each end, has been cloned into various vectors.
A A, Mercer +3 more
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Virus particles and antigens in experimental Orf scabs
Archiv f�r die gesamte Virusforschung, 1973Sequential observations of experimentally induced orf scabs on lambs revealed that complement-fixing antigens, precipitating antigens and virus particles all reached peak levels within one to two weeks. The most sensitive diagnostic technique was the detection of complement-fixing antigen.
C H, Romero-Mercado +4 more
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Heparin binding activity of orf virus F1L protein
Virus Research, 2004The orf virus is the type species of the Parapoxvirus genus and is the causative agent of contagious echtyma, a debilitating skin disease of sheep and goats, which can also affect man. The virus exhibits a restricted host range, even if it has been shown to bind to a wide range of tissues of non-permissive species.
SCAGLIARINI, ALESSANDRA +5 more
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