Results 181 to 190 of about 1,028,257 (352)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Tissue-engineered anterior segment eye cultures demonstrate hallmarks of conventional organ culture. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2023
Waxman S, Strzalkowska A, Wang C, Loewen R, Dang Y, Loewen NA.   +5 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Bovine Rectoanal Junction In Vitro Organ Culture Model System to Study Shiga Toxin-Producing Escherichia coli Adherence. [PDF]

Microorganisms, 2023
Kudva IT, Biernbaum EN, Cassmann ED, Palmer MV.   +3 more
europepmc   +1 more source

Bladder smooth muscle organ culture preparation maintains the contractile phenotype

, 2012
Tanchun Wang, Derek M. Kendig, Shaohua Chang, Danielle M. Trappanese, Samuel Chacko, Robert S. Moreland   +5 more
openalex   +2 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis. [PDF]

Nat Commun
Naim G, Romano-Zadaka H, Amidror S, Jessula Levy D, Cohen A, Sochen C, Gilberg H, Farah N, Rudenko V, Yarden Y, Feng M, Tsentsarevsky R, Brodie Z, Reich Y, Simon A, Toister E, Shoval I, Armon L, Schiller M, Mandel Y, Biton M, Yissachar N.   +21 more
europepmc   +1 more source

Galectin-3 and RAGE differentially control advanced glycation endproduct-induced collagen damage in murine intervertebral disc organ culture. [PDF]

JOR Spine, 2023
Gallate ZS, D'Erminio DN, Nasser P, Laudier DM, Iatridis JC.   +4 more
europepmc   +1 more source

Organ Culture [PDF]

, 2020
openaire   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source