Results 191 to 200 of about 1,034,083 (358)

Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture [PDF]

, 2020
Teresa Tsai, Ana M. Mueller‐Buehl, Yathavan Satgunarajah, Sandra Kuehn, H. Burkhard Dick, Stephanie C. Joachim   +5 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Conceptualization of an Ex Vivo Organ Culture (EVOC) Model for Human Seminoma: A Pilot Study. [PDF]

Int J Mol Sci
Demyashkin G, Shchekin V, Parshenkov M, Shegay P, Kaprin A.   +4 more
europepmc   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis. [PDF]

Nat Commun
Naim G, Romano-Zadaka H, Amidror S, Jessula Levy D, Cohen A, Sochen C, Gilberg H, Farah N, Rudenko V, Yarden Y, Feng M, Tsentsarevsky R, Brodie Z, Reich Y, Simon A, Toister E, Shoval I, Armon L, Schiller M, Mandel Y, Biton M, Yissachar N.   +21 more
europepmc   +1 more source

Tissue-engineered anterior segment eye cultures demonstrate hallmarks of conventional organ culture. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2023
Waxman S, Strzalkowska A, Wang C, Loewen R, Dang Y, Loewen NA.   +5 more
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

In vitro organ culture protocol for intact urogenital systems supporting gonadal differentiation. [PDF]

PLoS One
Whiteley SL, Holleley CE, Georges A.
europepmc   +1 more source

Galectin-3 and RAGE differentially control advanced glycation endproduct-induced collagen damage in murine intervertebral disc organ culture. [PDF]

JOR Spine, 2023
Gallate ZS, D'Erminio DN, Nasser P, Laudier DM, Iatridis JC.   +4 more
europepmc   +1 more source