Results 91 to 100 of about 680,344 (360)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Organ-on-a-disc: A platform technology for the centrifugal generation and culture of microphysiological 3D cell constructs amenable for automation and parallelization

open access: yesAPL Bioengineering, 2020
Organ-on-a-chip (OoC) systems have evolved to a promising alternative to animal testing and traditional cell assays in drug development and enable personalization for precision medicine.
Stefan Schneider   +4 more
doaj   +1 more source

Effect of Culture Technique of Ganoderma Australe Mycelia on Percentage Removal of Leachate Organics

open access: yesScientific Research Journal, 2016
Leachate (liquid pollutant), which is highly contaminated with organic matter and toxic substances is a major problem that arised from landfill. Biological methods have proven to be effective to remove organic matters that are abundant in leachate. This study is intended to compare the used of free mycelia and immobilized mycelia of the white-rot fungi,
Wan Razarinah Wan Abdul Razak   +2 more
openaire   +2 more sources

Isolation and primary cultures of human intrahepatic bile ductular epithelium [PDF]

open access: yes, 1988
A technique for the isolation of human intrahepatic bile ductular epithelium, and the establishment of primary cultures using a serum- and growth-factor-supplemented medium combined with a connective tissue substrata is described.
A. E. Sirica   +24 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Plant Secondary metabolites production by in vitro culture

open access: yesBiotecnología Vegetal, 2011
Plant cell and tissue cultures are considered as an alternative source to the whole plant for the production of valuable compounds. Undifferentiated cell cultures have been extensively studied, but a large interest has also been shown in hairy roots and ...
Naivy Pérez-Alonso, Elio Jiménez
doaj  

A novel, low-volume method for organ culture of embryonic kidneys that allows development of cortico-medullary anatomical organization.

open access: yesPLoS ONE, 2010
Here, we present a novel method for culturing kidneys in low volumes of medium that offers more organotypic development compared to conventional methods. Organ culture is a powerful technique for studying renal development.
David D R Sebinger   +5 more
doaj   +1 more source

Soft and Hard Implant Fabrication Using 3D-Bioplotting TM [PDF]

open access: yes, 2004
At the Freiburger Materialforschungszentrum we have developed a new process (3DBioplotting TM) that permits most kind of polymers and biopolymers to be used in 3D scaffold design, including hydrogels (e.g. collagen, agar), polymer melts (e.g. PLLA, PGA,
Carvalho, C., Landers, R., Mülhaupt, R.
core   +1 more source

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

open access: yesFEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau   +3 more
wiley   +1 more source

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